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Come Fan with UsMonday, June 22, 2026

Fantasy Scouting Report: San Francisco 49ers

What do the numbers say for the 49ers? Niners Nation lets us know.

The 49ers playoff hopes took a big hit last weekend, but they’ve still got plenty to play for this Monday Night. They face a Cardinals pass defense that has struggled a fair amount with a bend but don’t break style, meaning 49ers receivers certainly have some value, as does Alex Smith.

Alex Smith is coming off arguably the best game of his career, as he surpassed 300 yards passing for the first time. Smith has played quite well in the new shotgun offense the 49ers are employing and has seen his sack rate and interception rate both decline in the current offense. Unless you’ve got a Peyton Manning, Drew Brees type of QB, Alex Smith might actually be a great play this week at home in Candlestick Park without much pressure on him.
Vernon Davis remains the top 49ers receiving target, and probably the best tight end in fantasy football right now. While he’s had drop issues, the 49ers continue to target him a high amount of times, so he remains a must start over just about anybody else.
Michael Crabtree plays in his first Monday Night Football game and will be looking to put on a shoe in prime time. He is putting together a very solid rookie season. Although he has plenty of room for growth, he’s becoming a somewhat reliable fantasy performer. For now he’s no more than a #2 receiver, but more likely a flex guy.

Frank Gore has struggled rushing in the new offense, but remains a guy you have to stick with each week. Although his rushing numbers are down, he can always break a big one, and he remains a solid fixture in the passing game.

The 49ers defense has given up some big plays, but remains aggressive and worth starting. They face the always immobile Kurt Warner, and a less than stellar Cardinals offensive line, which could lead to some sacks. The 49ers and Cardinals always play solid games, so don’t expect a Cardinals blow out to kill those points allowed fantasy points.

49ers fans, join up with your countrymen at Niners Nation.

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