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Come Fan with UsTuesday, August 4, 2026

College football odds 2015, Week 10: Bama a TD favorite vs. LSU and more big lines

Alabama vs. LSU and TCU vs. Oklahoma State highlight a college football Week 10 betting card full of big games this Saturday.

John David Mercer-USA TODAY Sports

The Alabama Crimson Tide are 0-5 against the spread in their last five games at home. The Crimson Tide will attempt to pick up a win and cover in a key SEC West matchup this Saturday hosting the LSU Tigers.

Alabama is a 7-point home favorite on Saturday, according to sportsbooks monitored by OddsShark.com. Each of the last four games in this rivalry have gone Alabama's way, but two of the last three wins by the Crimson Tide came by a touchdown or less. LSU enters this game undefeated with a 7-0 SU and 4-3 ATS record on the season.

The picture in the Big 12 will get a bit clearer this week when the Oklahoma State Cowboys host the TCU Horned Frogs. Both teams enter this game with an 8-0 SU record while Oklahoma State holds the slight ATS advantage at 5-3 over TCU's 4-4. The home team is 3-0 SU and ATS over the last three games between these two teams, according to the OddsShark College Football Database. TCU is a 5-point road favorite this Saturday.

College football Week 10 betting lines

Navy at Memphis -9

Cincinnati at Houston -8.5

Notre Dame -7.5 at Pittsburgh

Iowa -7 at Indiana

LSU at Alabama -7

TCU -5 at Oklahoma State

View all Week 10 odds at OddsShark

The Notre Dame Fighting Irish have had an excellent season so far with a 7-1 SU and 6-2 ATS record, but the team has shown some vulnerability on the road. The Fighting Irish are 2-1 SU and 1-2 ATS on the road compared to a perfect 5-0 SU and ATS record at home. Notre Dame faces another road test this week against the Pittsburgh Panthers as a 7.5-point road favorite.

With another win and cover last week, the Iowa Hawkeyes have climbed into the Top 10 in the AP Top 25 poll. Iowa is 8-0 SU and 5-3 ATS this season and has won its games by an average margin of victory of 17.4 points per game. The Hawkeyes are a 7-point road favorite this Saturday visiting the Indiana Hoosiers. Indiana started the season off on a 4-0 SU and 3-1 ATS run, but has since gone 0-4 SU and 1-3 ATS over its last four games.

The Houston Cougars and Memphis Tigers will both try to stay undefeated this Saturday, heading into their big showdown next week. Houston is an 8.5-point favorite hosting Cincinnati and Memphis is a 9-point home favorite against Navy.

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