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Come Fan with UsTuesday, August 4, 2026

Ole Miss vs. Alabama odds: Tide seek revenge as betting favorite

Alabama will be seeking revenge for a loss to Mississippi last year when it hosts the Rebels as betting favorites this Saturday night.

Marvin Gentry-USA TODAY Sports

The Alabama Crimson Tide are 10-1 straight up in their last 11 games against the Mississippi Rebels with that one loss coming last year on the road. Alabama will be out for revenge this Saturday when it hosts Ole Miss at Bryant-Denny Stadium.

Alabama is a 7-point betting favorite at home according to sportsbooks monitored by OddsShark.com. This has been an active line early in the week with Ole Miss opening as an 8.5-point underdog, moving down to +6.5 and now back up to +7.

The one thing we know for sure about the Crimson Tide this season is that they have a true star at running back in Derrick Henry. No longer splitting carries with T.J. Yeldon, Henry has already racked up 243 rushing yards and six rushing touchdowns in just 31 carries this season.

The Heisman Trophy candidate figures to have a bigger workload this week against a quality opponent in Ole Miss.

The Crimson Tide are off to a 2-0 SU and 1-1 ATS start in 2015, winning and covering against Wisconsin and then winning but failing to cover at home against Middle Tennessee.

Ole Miss Rebels vs. Alabama Crimson Tide

When: Saturday, Sept. 19, 9:15 p.m. ET

Where: Bryant-Denny Stadium, Tuscaloosa, Ala.

Betting Line / Total: Alabama -7.0 / 51.5 Points

Rebels vs. Crimson Tide OddsShark Matchup Report

Mississippi seemed to have a dream season going last year with a 7-0 SU and ATS start, but the Rebels unraveled down the stretch in a 2-4 SU and 1-5 ATS free fall.

This year, the Rebels are off to a red-hot start again, going 2-0 SU and ATS out of the gate while outscoring their opponents, 149-24. Chad Kelly has looked sharp under center for Ole Miss with six touchdown passes and just one interception.

Now the real test begins. Fans and bettors will soon find out if the blowouts over Tennessee-Martin and Fresno State were indicative of a strong team or just weak opponents. Ole Miss is 7-3 ATS in its last 10 games against Alabama per the OddsShark College Football Database.

Saturday’s total is set at 51.5 points. The total has gone UNDER in each of Alabama’s last four home games against Ole Miss.

This game is a tricky one to call coming so early in the year with little to go on. But taking Alabama’s history in this rivalry, home field, and a chip on the Crimson Tide’s shoulder from last year’s loss into account, the Crimson Tide at -7 look to be the play.

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