Skip to main content
Come Fan with UsSaturday, June 20, 2026

Auburn vs. Louisville odds: Take the Tigers to win big

Auburn starts what many project to be a promising campaign this Saturday. This article was provided to SB Nation by OddsShark.com.

John Reed-USA TODAY Sports

The Louisville Cardinals have been a consistent thorn in the side of SEC teams recently with a 5-1 straight up and 4-2 against the spread record in their last six meetings. The Cardinals will try to score an upset this Saturday when they face the No. 6 Auburn Tigers at the Georgia Dome.

Louisville is a 10.5-point betting underdog for Saturday's showdown, according to sportsbooks monitored by OddsShark.com. The Cardinals are a perfect 7-0 ATS in their last seven games as a double-digit underdog, with outright wins in their last two.

Saturday’s total for the Cardinals vs. Tigers betting matchup is set at 55.5 points. The OVER is 4-2-1 in Auburn’s last seven games and 4-1-1 in Louisville’s last six games, according to the OddsShark College Football Database.

In their first season in the ACC last year, the Cardinals passed the test with a respectable 9-4 SU and 7-6 ATS record. The Cardinals won games with an elite defense last year, but that defense lost seven starters this offseason and could take a step back in 2015.

Dual-threat quarterback Reggie Bonnafon will need to take control of this offense for the Cardinals to have success this season. Louisville ended last year on a 2-4 ATS run.

Auburn looked to be on its way to another strong season last year with a 5-0 SU and 3-2 ATS start that included a 41-7 win at home over LSU. However, the wheels fell off over the second half of the season as the Tigers went just 3-5 SU and 1-7 ATS.

Things should be much better in 2015. Jeremy Johnson takes over at quarterback and has a bigger arm than Nick Marshall did. On defense, Will Muschamp should make an immediate impact as defensive coordinator. The Tigers are 1-3 SU and 2-2 ATS in their last four games against ACC opponents.

A dual-threat quarterback like Bonnafon would have likely had a field day on Auburn’s awful defense last season. Muschamp’s new defensive schemes will be put to the test right away. But even if Auburn’s defense isn’t perfect, Gus Malzahn’s fast-paced offense should put up big numbers against an inexperienced Cardinals squad. Take the Tigers to win and cover the 10.5-point spread.

Louisville Cardinals vs. Auburn Tigers

When: Saturday, September 5, 3:30pm ET

Where: Georgia Dome, Atlanta, Georgia

Betting Line / Total: Auburn -10.5 / 55.5 Points

Cardinals vs. Tigers OddsShark Matchup Report

College Football
The NCAA can appeal Brendan Sorsby’s shocking reinstatement, but Texas law isn’t on their sideThe NCAA can appeal Brendan Sorsby’s shocking reinstatement, but Texas law isn’t on their side
College Football

A big can of worms has been opened in college sports

By Mark Schofield
College Football
Here’s your first look at ‘College Football 27’ and ‘Madden 27’Here’s your first look at ‘College Football 27’ and ‘Madden 27’
College Football

Mascot game! Tush push!

By James Dator
NFL
Brendan Sorsby’s gambling allegations could end his college football career. Is NFL Supplemental Draft next?Brendan Sorsby’s gambling allegations could end his college football career. Is NFL Supplemental Draft next?
NFL

Brendan Sorsby calls out NCAA hypocrisy as his football future is uncertain

By Mark Schofield
College Football
NAACP urges black athletes to reject recruiting in racially gerrymandered statesNAACP urges black athletes to reject recruiting in racially gerrymandered states
College Football

The NAACP is asking athletes to take up the fight for voting rights.

By James Dator
College Football
Oregon coach asks recruits about their favorite ice cream, and it actually makes senseOregon coach asks recruits about their favorite ice cream, and it actually makes sense
College Football

Oregon coaches have a strange question for potential recruits.

By Mark Schofield
NFL
Why Jeremiyah Love brings top-5 value to NFL Draft as a RBWhy Jeremiyah Love brings top-5 value to NFL Draft as a RB
NFL

The Notre Dame star is the rare running back worth a top-10 or even top-5 pick.

By Mark Schofield