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Come Fan with UsMonday, July 6, 2026

Interleague Betting Favors Underdogs On Day 1

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For the third day in a row, baseball underdogs on the MLB betting lines won more games than they lost, turning a healthy profit for savvy Vegas players.

It didn't seem to matter that the scene turned to interleague play. Dogs barked to the tune of 8-7 Friday, although the biggest moneyline winner was the Seattle Mariners, who were only getting +125 at the Colorado Rockies.

There were only a few big lines for this season's first day of interleague play. Over the last three days, baseball underdogs are 28-17. How much longer can that trend, a reversal of earlier trends that saw favorites win at a steady pace, continue?

Among Saturday's baseball betting matchups Ivan Nova and the Yankees are -165 home favorites over Homer Bailey and the Reds (1 pm Eastern); Anibel Sanchez and the Marlins are –115 road favorites at Jeanmar Gomez and Cleveland (4 pm Eastern); Ryan Dempster and the Cubs are -135 faves over John Danks and the White Sox at Wrigley (7:15 Eastern); and NL Cy Younger Clayton Kershaw and the Kemp-less Dodgers are -145 Chavez Ravine favorites over Jake Westbrook and the Cardinals (10:10 Eastern).

Here's a quick look at all of Saturday's baseball betting action, with MLB odds courtesy of SB Nation.

Cincinnati +159 at NY Yankees -166, Total 9.5 - Homer Bailey (1-3) | Ivan Nova (4-1) | Matchup Report | SBNation MLB Odds
Trends: The total has gone UNDER in 6 of Cincinnati’s last 7 games when playing NY Yankees
The total has gone UNDER in 6 of NY Yankees’s last 7 games

NY Mets +188 at Toronto -197, Total 8.5 - Miguel Batista (1-1) | Brandon Morrow (4-2) | Matchup Report | SBNation MLB Odds
Trends: The total has gone OVER in 5 of NY Mets’s last 5 games on the road
The total has gone OVER in 5 of Toronto’s last 6 games when playing at home against NY Mets

Oakland +126 at San Francisco -131, Total 7 - Tyson Ross (2-3) | Ryan Vogelsong (1-2) | Matchup Report | SBNation MLB Odds
Trends: The total has gone UNDER in 5 of Oakland’s last 7 games
San Francisco is 5-0 SU in its last 5 games when playing at home against Oakland

Pittsburgh +152 at Detroit -157, Total 8 - AJ Burnett (1-2) | Drew Smyly (1-0) | Matchup Report | SBNation MLB Odds
Trends: The total has gone OVER in 7 of Pittsburgh’s last 9 games on the road
Detroit is 5-1 SU in its last 6 games when playing at home against Pittsburgh

Miami -113 at Cleveland +108, Total 7.5 - Anibal Sanchez (2-1) | Jeanmar Gomez (2-2) | Matchup Report | SBNation MLB Odds
Trends: Miami is 10-2 SU in its last 12 games on the road
Cleveland is 4-1 SU in its last 5 games

Seattle +137 at Colorado -142, Total 9 - Jason Vargas (4-3) | Christian Friedrich (1-0) | Matchup Report | SBNation MLB Odds
Trends: The total has gone UNDER in 5 of Seattle’s last 6 games when playing on the road against Colorado
The total has gone UNDER in 5 of Colorado’s last 6 games when playing at home against Seattle

Minnesota +157 at Milwaukee -163, Total 8 - Carl Pavano (2-3) | Yovani Gallardo (2-4) | Matchup Report | SBNation MLB Odds
Trends: The total has gone OVER in 5 of Minnesota’s last 6 games when playing Milwaukee
Milwaukee is 6-1 SU in its last 7 games when playing at home against Minnesota

Atlanta -101 at Tampa Bay -104, Total 8.5 - Randall Delgado (2-3) | Alex Cobb (0-0) | Matchup Report | SBNation MLB Odds
Trends: Atlanta is 5-1 SU in its last 6 games on the road
The total has gone UNDER in 4 of Tampa Bay’s last 5 games when playing at home against Atlanta

Texas -168 at Houston +161, Total 9 - Derek Holland (3-2) | Lucas Harrell (2-3) | Matchup Report | SBNation MLB Odds
Trends: Texas is 9-1 SU in its last 10 games when playing on the road against Houston
The total has gone UNDER in 5 of Houston’s last 6 games at home

Boston -106 at Philadelphia +101, Total 7.5 - Jon Lester (2-3) | Joe Blanton (4-2) | Matchup Report | SBNation MLB Odds
Trends: The total has gone UNDER in 4 of Boston’s last 5 games
Philadelphia is 5-0 SU in its last 5 games

Baltimore +103 at Washington -108, Total 7 - Jason Hammel (4-1) | Ross Detwiler (3-2) | Matchup Report | SBNation MLB Odds
Trends: Baltimore is 5-0 SU in its last 5 games on the road
The total has gone OVER in 7 of Washington’s last 8 games at home

Chi White Sox +126 at Chi Cubs -131 - John Danks (2-4) | Ryan Dempster (0-1) | Matchup Report | SBNation MLB Odds
Trends: The total has gone UNDER in 5 of Chi White Sox’s last 5 games when playing Chi Cubs
The total has gone UNDER in 5 of Chi Cubs’s last 5 games when playing Chi White Sox

Arizona -108 at Kansas City +103, Total 8.5 - Ian Kennedy (3-3) | Bruce Chen (2-4) | Matchup Report | SBNation MLB Odds
Trends: Arizona is 5-0 SU in its last 5 games when playing Kansas City
The total has gone UNDER in 6 of Kansas City’s last 9 games

LA Angels at San Diego - Dan Haren (1-4) | Eric Stults (0-0) | Matchup Report | SBNation MLB Odds
Trends: LA Angels are 5-1 SU in their last 6 games when playing San Diego
The total has gone OVER in 4 of San Diego’s last 5 games

St. Louis +136 at LA Dodgers -141, Total 6 - Jake Westbrook (4-2) | Clayton Kershaw (3-1) | Matchup Report | SBNation MLB Odds
Trends: The total has gone OVER in 7 of St. Louis’s last 8 games
LA Dodgers are 5-0 SU in their last 5 games when playing St. Louis

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