Been waiting all week for Thursday night. That’s how the saying goes, right? This week the biggest game on the NFL slate comes from Thursday Night Football between the Rams and Seahawks, in an NFC West divisional matchup that could settle who wins the west and earns a first round bye, and who could find themselves in a road wild cad game.
NFL Expert Picks for Week 16 of 2025
Here are our picks for Week 16.
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When it comes to Thursday night we have a totally split panel, with five thinking the Rams will win, and five believing in the Seahawks. That’s not the only critical game of the week with the Panthers and Buccaneers facing off in what could determine the NFC South, as well as the Jaguars and Broncos battling atop the AFC.
Here are our picks for Week 16.
Week 16 | Mookie Alexander | James Dator | Chet Gresham | Brandon Lee Gowton | Jared Mueller | R.J. Ochoa | Ricky O’Donnell | Mark Schofield | Nick Simon | Matt Warren |
|---|---|---|---|---|---|---|---|---|---|---|
| TNF: Rams vs. Seahawks | Rams | Rams | Seahawks | Rams | Seahawks | Seahawks | Rams | Seahawks | Rams | Seahawks |
| Eagles vs. Commanders | Eagles | Eagles | Eagles | Eagles | Eagles | Eagles | Eagles | Eagles | Eagles | Eagles |
| Packers vs. Bears | Bears | Packers | Packers | Packers | Bears | Bears | Bears | Bears | Bears | Packers |
| Chargers vs. Cowboys | Chargers | Cowboys | Chargers | Cowboys | Chargers | Chargers | Cowboys | Chargers | Cowboys | Chargers |
| Vikings vs. Giants | Vikings | Vikings | Vikings | Vikings | Vikings | Vikings | Giants | Vikings | Vikings | Vikings |
| Bengals vs. Dolphins | Bengals | Bengals | Dolphins | Bengals | Bengals | Bengals | Bengals | Bengals | Bengals | Bengals |
| Buccaneers vs. Panthers | Panthers | Panthers | Bucs | Buccaneers | Panthers | Panthers | Bucs | Panthers | Buccaneers | Panthers |
| Jets vs. Saints | Saints | Saints | Saints | Saints | Saints | Saints | Saints | Saints | Saints | Saints |
| Bills vs. Browns | Bills | Bills | Bills | Bills | Bills | Bills | Bills | Bills | Bills | Bills |
| Chiefs vs. Titans | Titans | Titans | Chiefs | Chiefs | Chiefs | Titans | Chiefs | Titans | Chiefs | Chiefs |
| Jaguars vs. Broncos | Broncos | Broncos | Broncos | Jaguars | Broncos | Broncos | Broncos | Broncos | Broncos | Broncos |
| Falcons vs. Cardinals | Falcons | Falcons | Cardinals | Falcons | Cardinals | Falcons | Falcons | Falcons | Falcons | Falcons |
| Raiders vs. Texans | Texans | Texans | Texans | Texans | Texans | Texans | Texans | Texans | Texans | Texans |
| Steelers vs. Lions | Lions | Lions | Steelers | Lions | Lions | Lions | Lions | Steelers | Lions | Steelers |
| SNF: Patriots vs. Ravens | Patriots | Patriots | Patriots | Ravens | Patriots | Patriots | Ravens | Patriots | Patriots | Ravens |
| MNF: 49ers vs. Colts | 49ers | 49ers | 49ers | 49ers | Colts | 49ers | 49ers | 49ers | 49ers | 49ers |
| 2025 Pick record | 127-79-1 | 129-77-1 | 131-75-1 | 131-75-1 | 115-91-1 | 125-81-1 | 140-66-1 | 132-74-1 | 128-78-1 | 136-70-1 |
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