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Come Fan with UsTuesday, June 23, 2026

NFL Picks Week 5: Philadelphia Eagles Vs. San Francisco 49ers

SB Nation bloggers Brian Galliford (Buffalo Rumblings), Jason Kirk (SB Nation Atlanta) and Dave Halprin (Blogging The Boys) have taken a look at the schedule and given us their NFL Week 5 picks.

Philadelphia Eagles (2-2) vs. San Francisco 49ers (0-4)

Line: 49ers are 3.5 point favorites.

The pick: Eagles

Brian Galliford: Avert your eyes: this one could be fairly ugly sans Michael Vick. San Fran's offense is too stagnant to win this game.

Jason Kirk: When Mike Singletary’s madness and Andy Reid’s time management combine, they form Les Miles. Please don’t bet on the result.

The pick: 49ers

Dave Halprin: The 49ers haven’t met their pre-season expectations, in fact they’ve been terrible, but this week they finally see the win column.

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