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Come Fan with UsSaturday, June 20, 2026

NFL Week 4 Preview, Prediction: Arizona Cardinals Vs. San Diego Chargers

Arizona Cardinals (2-1) vs. San Diego Chargers (1-2)

When: 4:00 p.m. Sunday, FOX

SB Nation Cardinals: Revenge Of The Birds

SB Nation Chargers: Bolts From The Blue

Breakdown: The NFL is usually a battle of quarterbacks and you've got one of the league's worst (Derek Anderson) and one of the league's best (Philip Rivers). The Chargers offense hasn't had a ton of problems this season and I don't see that changing against the Cardinals.

Player to Watch: Ryan Mathews. He's returning to practice for the Chargers and looks poised to play on Sunday. He's their top running back and will probably want a big game to get back in the swing of things.

Line: Chargers are eight point favorites.
Prediction: Take the Chargers though home field advantage doesn’t matter much. They’ll win by a touchdown at the minimum.

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