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Come Fan with UsFriday, July 3, 2026

College football opening lines, Week 4: Notre Dame, Stanford favored in big games

Notre Dame never covers the spread at Michigan State, and Arizona State never covers at Stanford. A pair of 6-point spreads on the college football opening odds menu offer good wagering value.

Mike Carter-US PRESSWIRE

There are many constants in the world college football, and one of them is that Michigan State will cover the spread at home against Notre Dame. So it’s not a huge surprise that the Spartans open as 6-point favorites in the annual battle against the Fighting Irish in one of Week 4’s most important matchups.

Texas A&M gets a cupcake after its main course defeat at the hands of Alabama Saturday. They opened as four-TD chalk against a SMU team that barely defeated Montana State. Expect the line to climb in this one, as the Aggies have scorched SMU 160-25 in three games since 2005.

Stanford finally gets its home opener, but it’s a tough task in Arizona State. They opened as 6.5-point chalk (early line courtesy of 5Dimes) and have handled the Sun Devils at home over the years (5-1 ATS in the past decade).

And in an important SEC clash, LSU opened as 14-point home chalk against Auburn, a team that has not won here since 1999. They have lost six straight and the betting line points to more of the same in 2013.

Check out the opening college football lines, courtesy of OddsShark.com. Some games don’t have numbers yet, so be sure to visit OddsShark throughout the week for updates.

Thursday

Clemson -14 at North Carolina State +14 - Matchup Report
Trends: Clemson is 10-1 SU in its last 11 games. The total has gone UNDER in North Carolina State’s last 5 home games.

Friday

Boise State +4 at Fresno State -4 - Matchup Report
Trends: Boise State is 5-0 SU in its last 5 games when playing Fresno State. Fresno State is 8-1 SU in its last 9 games at home.

Saturday

Vanderbilt -31.5 at Massachusetts +31.5 - Matchup Report

Trends: Vanderbilt is 8-2 SU in its last 10 games. The total has gone UNDER in 5 of Massachusetts’s last 6 games.

Michigan -17.5 at Connecticut +17.5 - Matchup Report

Trends: Michigan is 6-2 SU in its last 8 games. Connecticut is 15-8 SU in its last 23 games at home.

Marshall +11 at Virginia Tech -11 - Matchup Report

Trends: The total has gone OVER in 5 of Marshall’s last 7 games on the road. Virginia Tech is 5-1 SU in its last 6 games.

North Carolina +6 at Georgia Tech -6 - Matchup Report
Trends: The total has gone OVER in 5 of North Carolina’s last 6 games when playing on the road against Georgia Tech. Georgia Tech is 5-0 SU in its last 5 games when playing at home against North Carolina.

Western Michigan +17 at Iowa -17 - Matchup Report
Trends: The total has gone UNDER in 5 of Western Michigan’s last 5 games. The total has gone OVER in 4 of Iowa’s last 6 games.

Wake Forest -4 at Army +4 - Matchup Report
Trends: The total has gone UNDER in 5 of Wake Forest’s last 5 games on the road. The total has gone UNDER in 4 of Army’s last 6 games.

Florida International +42 at Louisville -42 - Matchup Report
Trends: The total has gone OVER in 6 of FIU’s last 7 games on the road. Louisville is 5-0 SU in its last 5 games.

North Texas +31.5 at Georgia -31.5 - Matchup Report
Trends: The total has gone UNDER in 5 of North Texas’s last 7 games. Georgia is 10-1 SU in its last 11 games at home.

Pittsburgh -4 at Duke +4 - Matchup Report
Trends: The total has gone UNDER in 8 of Pittsburgh’s last 10 games on the road. The total has gone OVER in 5 of Duke’s last 7 games at home.

Ball State -11.5 at Eastern Michigan +11.5 - Matchup Report

Trends: Ball State is 7-1 SU in its last 8 games when playing Eastern Michigan. The total has gone OVER in 6 of Eastern Michigan’s last 7 games when playing Ball State.

Rice +2 at Houston -2 - Matchup Report

Trends: Rice is 6-1 SU in its last 7 games. Houston is 6-2 SU in its last 8 games when playing Rice.

Michigan State +7 at Notre Dame -7 - Matchup Report
Trends: Michigan State is 5-0 SU in its last 5 games. Notre Dame is 10-1 SU in its last 11 games at home.

Kent State +19.5 at Penn State -19.5 - Matchup Report

Trends: Kent State is 6-1 SU in its last 7 games on the road. The total has gone OVER in 5 of Penn State’s last 5 games at home.

Purdue +23.5 at Wisconsin -23.5 - Matchup Report
Trends: The total has gone OVER in 5 of Purdue’s last 7 games when playing on the road against Wisconsin. Wisconsin is 5-0 SU in its last 5 games when playing Purdue.

Utah State +7 at Southern Cal -7 - Matchup Report

Trends: The total has gone OVER in 5 of Utah State’s last 5 games on the road. The total has gone UNDER in 9 of Southern Cal’s last 11 games at home.

Tennessee +14.5 at Florida -14.5 - Matchup Report
Trends: The total has gone OVER in 5 of Tennessee’s last 6 games on the road. Florida is 5-0 SU in its last 5 games when playing Tennessee.

West Virginia +5 at Maryland -5 - Matchup Report

Trends: The total has gone UNDER in 5 of West Virginia’s last 5 games. The total has gone OVER in 4 of Maryland’s last 5 games.

Louisiana-Monroe +27 at Baylor -27 - Matchup Report

Trends: Louisiana-Monroe is 5-2 SU in its last 7 road games. Baylor is 5-0 SU in its last 5 games.

Cincinnati -21.5 at Miami (Ohio) +21.5 - Matchup Report
Trends: Cincinnati is 5-0 SU in its last 5 games when playing Miami (Ohio). The total has gone UNDER in 7 of Miami (Ohio)‘s last 8 games.

Arkansas State -6 at Memphis +6 - Matchup Report
Trends: Arkansas State is 10-1 SU in its last 11 games. Memphis is 5-1 SU in its last 6 games when playing at home against Arkansas State.

Louisiana-Lafayette -7.5 at Akron +7.5 - Matchup Report
Trends: Louisiana-Lafayette is 5-2 SU in its last 7 games. The total has gone UNDER in 9 of Akron’s last 10 games.

Colorado State +38.5 at Alabama -38.5 - Matchup Report

Trends: The total has gone OVER in 5 of Colorado State’s last 6 games on the road. Alabama is 5-0 SU in its last 5 games.

Arizona State +7.5 at Stanford -7.5 - Matchup Report
Trends: Arizona State is 5-0 SU in its last 5 games. Stanford is 5-0 SU in its last 5 games.

Southern Methodist +28.5 at Texas A&M -28.5 - Matchup Report

Trends: The total has gone OVER in 7 of Southern Methodist’s last 10 games. Texas A&M is 8-1 SU in its last 9 games.

Texas State +25.5 at Texas Tech -25.5 - Matchup Report
Trends: The total has gone UNDER in 8 of Texas State’s last 9 games on the road. Texas Tech is 5-1 SU in its last 6 games at home.

Oregon State -11 at San Diego State +11 - Matchup Report

Trends: The total has gone OVER in 5 of Oregon State’s last 6 games on the road. The total has gone UNDER in 5 of San Diego State’s last 5 games at home.

Auburn +16.5 at LSU -16.5 - Matchup Report
Trends: Auburn is 4-1 SU in its last 5 games. LSU is 5-0 SU in its last 5 games when playing at home against Auburn.

Missouri -4.5 at Indiana +4.5 - Matchup Report
Trends: The total has gone OVER in 4 of Missouri’s last 5 games. The total has gone OVER in 5 of Indiana’s last 6 games.

Kansas State +5.5 at Texas -5.5 - Matchup Report
Trends: Kansas State is 5-0 SU in its last 5 games when playing Texas. The total has gone OVER in Texas’s last 5 games.

UTSA +3 at Texas El Paso -3 - Matchup Report
Trends: UTSA is 6-0-1 ATS in its last 7 games. The total has gone OVER in Texas El Paso’s last 5 games.

Hawaii +12 at Nevada -12 - Matchup Report
Trends: The total has gone UNDER in 4 of Hawaii’s last 5 games. Nevada is 5-1 SU in its last 6 games when playing at home against Hawaii.

New Mexico State +41.5 at UCLA -41.5 - Matchup Report

Trends: The total has gone OVER in 5 of New Mexico State’s last 5 games. The total has gone OVER in 4 of UCLA’s last 5 games at home.

Idaho +30.5 at Washington State -30.5 - Matchup Report
Trends: The total has gone UNDER in 4 of Idaho’s last 6 games on the road. Washington State is 5-0 SU in its last 5 games when playing Idaho.

More from SB Nation:

What we learned from the Alabama-Texas A&M classic

Trying to explain that insane Wisconsin-Arizona State ending

All our coverage from Week 3’s Saturday

Spencer Hall’s top 25 review

Would coaches rather replace Mack Brown or Lane Kiffin?

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