Skip to main content
Come Fan with UsFriday, July 3, 2026

Oklahoma vs. Notre Dame betting odds and pick: Sooners to take South Bend

Oklahoma has lost two in a row vs Notre Dame, but the odds say the Sooners will beat the Irish Saturday. The Odds Shark prediction agrees with the betting line.

Wesley Hitt

The Oklahoma Sooners are 3-0 straight up and 2-1 against the spread in 2013, and will try to stay undefeated Saturday when they visit the Notre Dame Fighting Irish at South Bend. The Sooners are a 3.5-point road favorite to beat the Irish, who have defeated them in both meetings since 1999.

After starting the season with quarterback Trever Knight over Blake Bell, Bell took over the starting job at home against Tulsa two weeks ago and played brilliantly. Better known for his rushing ability, Bell showed that he could pass well too, racking up 413 passing yards and four touchdown passes with no interceptions against the Golden Hurricane.

With the defense allowing just nine points per game through the first three games of the season, Oklahoma is looking like a serious contender for the Big 12 title and maybe more after being the third betting choice in Big 12 futures back in August.

Notre Dame has clearly lost a step from last year, going 0-3-1 ATS so far while just barely getting by Purdue and Michigan State and losing outright to Michigan. Still, the Irish are 3-1 SU, and have looked solid on offense with quarterback Tommy Rees under center. While they were virtually impossible to run on in the regular season in 2012, the Fighting Irish have allowed over 115 rushing yards in three of their four games this season.

Oklahoma hosted Notre Dame last year and was an 11.5-point favorite at home. The Fighting Irish picked up a signature win in that one, crushing the Sooners 30-13. It is difficult to see them repeating that performance on defense with this year’s squad, but can they solve the Sooners’ defense again? That game went under the posted total of 48.

College football odds database

Oklahoma has a tendency to drop a game or two that it is favored in every year, and this could be that spot this year. But with what looks to be an elite defense, a solid dual-threat quarterback under center, and a week off to prepare, we think that the Sooners have the goods to take care of business in South Bend.

PICK: Oklahoma -3.5 | Computer Prediction: 34-23 Sooners (from Odds Shark college football picks engine)

More from SB Nation:

Your full Week 5 TV schedule guide

Advanced stats pick the winner of every game

LSU vs. Georgia and the revenge of the SEC offense

Longform: Inside Chip Kelly’s offense at New Hampshire

Pay-for-play debate heating up

Today’s college football news headlines

Sports Odds, Lines And Betting News
6 Super Bowl 60 prop bet picks for Seahawks vs. Patriots6 Super Bowl 60 prop bet picks for Seahawks vs. Patriots
Sports Odds, Lines And Betting News

There are some fun prop bets on the board for Super Bowl 60

By Bill Williamson
NFL
What Super Bowl odds tell us about the final four teamsWhat Super Bowl odds tell us about the final four teams
NFL

The Seahawks head into the conference championships as the Super Bowl 60 favorite. We break down the odds of the final four teams.

By David Fucillo
NFL
Opening odds for 49ers-Seahawks in 2026 NFC Divisional roundOpening odds for 49ers-Seahawks in 2026 NFC Divisional round
NFL

The NFC Divisional round is set. We break down the opening odds for 49ers-Seahawks.

By Nick Simon
Sports Odds, Lines And Betting News
Opening odds for Rams-Bears in 2026 NFC Divisional roundOpening odds for Rams-Bears in 2026 NFC Divisional round
Sports Odds, Lines And Betting News

The NFC Divisional round is set. We break down the opening odds for Rams-Bears.

By Nick Simon
Women's College Basketball
3 women’s college basketball teams with enticing 2026 national championship odds3 women’s college basketball teams with enticing 2026 national championship odds
Women's College Basketball

UConn and South Carolina are the favorites, but other women’s college basketball teams have enticing title odds.

By Mitchell Northam
Men's College Basketball
March Madness odds: Chances for every team in the 2025 NCAA tournament to win the titleMarch Madness odds: Chances for every team in the 2025 NCAA tournament to win the title
Men's College Basketball

Cooper Flagg leads Duke to be the tournament favorite.

By James Dator and David Fucillo