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Come Fan with UsWednesday, July 1, 2026

Chargers a big favorite in NFL Week 6 Opening Odds

San Diego is among the hot teams on the road on Sunday’s NFL betting card.

Stephen Dunn

The San Diego Chargers are 10-1 ATS and 9-2 SU over their last 11 games. The Chargers will be one of the biggest favorites on the board this week visiting the lowly Oakland Raiders.

Riding a 4-0 SU and ATS streak, the Chargers are a 7-point road favorite for Sunday, according to sportsbooks monitored by OddsShark.com. Oakland is 0-4 SU and ATS in its last four games as a home underdog and 1-5 SU and ATS in its last six games coming off a bye week.

The Denver Broncos visit the New York Jets as another big road favorite for Sunday going off at -8 in the Meadowlands. Denver is 7-3 ATS in its last 10 games as a road favorite. The Jets have put up a better fight than the Raiders as a home underdog recently, with a 3-1 SU and ATS record in their last four games as a home dog.

The Cincinnati Bengals are a perfect 11-0 SU and ATS in their last 11 regular-season home games. This Sunday, the Bengals host the Carolina Panthers as 7-point home favorites at sportsbooks monitored by OddsShark.com. Carolina has fared well in the role of road underdog recently, with an 8-2 ATS record in its last 10 games as an underdog away from home.

Buffalo hosts New England on Sunday in a game that the Bills would love to win outright as a 3-point home underdog. New England has completely owned its AFC rival over the last decade with a 20-1 SU record over the last 21 meetings between these two teams. Buffalo holds a slight 5-4-1 ATS edge in the last 10 games in this series, but has managed only one outright win over that stretch.

On Monday night, the San Francisco 49ers visit the St. Louis Rams. St. Louis was 5-1 ATS in its previous six games against San Francisco before last season, when the 49ers swept the season series and went 2-0 SU and ATS against the Rams. San Francisco is a 3-point road favorite on Monday night.

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