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Come Fan with UsSaturday, June 20, 2026

Mississippi State vs. Alabama odds, guide, and prediction

Mississippi State faces its toughest road test yet going up against the Alabama Crimson Tide.

John David Mercer-USA TODAY Sports

The Alabama Crimson Tide host Mississippi State at Bryant-Denny Stadium at 3:30 p.m. ET on Saturday (CBS). The Crimson Tide are 11-2 SU in their last 13 games against Mississippi State and 6-0 SU in the last six meetings between these two teams.

Alabama will try to hand Mississippi State its first loss of the season.

Alabama is a seven-point home favorite, according to sportsbooks monitored by OddsShark. While the Crimson Tide do have a good chance of winning this game outright at home, Mississippi State’s track record this season suggests that the Bulldogs can keep this game within a touchdown.

[ The Bulldogs are #3 in the latest Odds Shark NCAA Power Poll - where is Alabama? ]

With the team’s playoff hopes hanging in the balance down 13-10 in the closing moments of last Saturday’s road game against LSU, Blake Sims led Alabama down the field for a game-tying drive and put the team up 20-13 in overtime to seal a win against the Tigers.

Even with the unlikely ATS push as a seven-point road favorite, Alabama has only a 2-6-1 ATS record to go along with its 8-1 SU record. Alabama is 7-0 SU and ATS in its last seven home games against SEC opponents.

OddsShark Computer Prediction: Mississippi State 27.3, Alabama 25.4

Since starting the season off 6-0 SU and 5-1 ATS, Mississippi State is 0-3 ATS over its last three wins. The Bulldogs have kept winning, though, to improve their SEC-best winning streak to 12 wins dating back to last season.

Dak Prescott is currently going off at 4/1 to win the Heisman Trophy at Bovada.lv, and he could make a statement on Saturday with a road upset. Mississippi State is 4-1 ATS in its last five road games and 3-1 ATS in its last four games as a road underdog.

Alabama is 13-0 SU in its last 13 games as a home favorite, and Mississippi State is 2-10 SU in its last 12 as a road underdog. The Bulldogs make for a risky moneyline play, but the No. 1 team in the country has been strong on both sides of the ball all year long. It is difficult to see State going down without a hard fight in a close game at +7.

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