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Come Fan with UsWednesday, July 1, 2026

Colts vs. Cowboys: Betting odds, spread, preview, and prediction

The Indianapolis Colts face a road test against the Dallas Cowboys Sunday.

Brian Spurlock-USA TODAY Sports

The Indianapolis Colts are just 2-6 SU and 3-5 ATS in their last eight games as a road underdog. The Colts will try to pick up a tough road win this Sunday when they visit the Dallas Cowboys.

Indianapolis is a 3-point road underdog at sportsbooks monitored by OddsShark.com. With DeMarco Murray possibly out with an injury this week, Indianapolis could take advantage and pick up an upset win as a 3-point underdog.

OddsShark Computer Prediction: Indianapolis 32.1, Dallas 27.9

Since starting the season off 0-2 SU and 1-1 ATS, it has been pretty smooth sailing for the Indianapolis Colts. Andrew Luck leads the NFL in passing yards and passing touchdowns and the offense ranks third in both total yards and scoring on the season. Over their last 12 games, the Colts are 10-2 SU and 8-3-1 ATS including a 17-10 win over Houston last week that locked up the AFC South title. Indianapolis is 3-1 SU and ATS in its last four games against NFC opponents.

Dallas hosts Indianapolis at AT&T Stadium at 4:25 p.m. ET on Sunday afternoon.

The Cowboys dug deep last Sunday night and came away with an impressive 38-27 road win over the Philadelphia Eagles, improving to 10-4 SU and 8-6 ATS on the year and taking over first place in the NFC East. Interestingly enough, the Cowboys have been far better on the road this season with a 7-0 SU and 6-1 ATS record than they have been at home where they are 3-4 SU and 2-5 ATS. In its last eight games as a home favorite, Dallas is just 1-7 ATS and 4-4 SU.

Sunday's total is set at 55 points on the Week 16 NFL betting lines. The OVER is 9-1 in Indianapolis's last 10 road games against NFC teams and 4-1 in the Colts' last five games as a road underdog.

This game has the makings of a great one between two explosive offenses, but the 23rd-ranked passing defense of Dallas could be a hindrance against Andrew Luck's passing attack. In what could end up being a close game that could go either way, Indianapolis has solid value getting a full +3 in this one.

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