Skip to main content
Come Fan with UsSaturday, June 20, 2026

Clemson at Florida State betting trends and Pick

Florida State lays nearly three touchdowns at the feel of Clemson in college football betting action this week (8 p.m. ET Saturday, ABC).

Streeter Lecka

The Clemson Tigers are 7-2 ATS in their last nine games against the Florida State Seminoles. After a blowout loss to Florida State last year, the Tigers were going to try to bounce back as a 20.5-point road underdog visiting the Seminoles this Saturday night, but that number shrank Wednesday when Jameis Winston was suspended for the first half of this game.

Picking against the Florida State Seminoles is a scary proposition, but Clemson’s history against this team and FSU’s slow start to the season suggest that there could be some value in Clemson at +16.5 at sportsbooks monitored by OddsShark.com this week.

Odds Shark Computer Prediction: 50-29 Florida State

Breaking in new starters at quarterback, running back and multiple wide receiver spots, Clemson was faced with the daunting task of playing against Georgia on the road in its season opener. Clemson lost that game, 45-21, before bouncing back with a 73-7 win and cover over South Carolina State. The inexperienced Tigers offense will get more trial by fire this week on the road against the nation’s best team.

Florida State is the team to beat in college football until another team proves otherwise, amassing an 18-0 SU and 12-6 ATS record over 18 games since December 2012. But while the Seminoles were nearly flawless through their undefeated 14-0 SU and 11-3 ATS run in 2013, Florida State is off to a rocky 0-2 ATS start so far this season. The Seminoles narrowly escaped with a 37-31 win at Oklahoma State, and didn’t look much sharper in a 37-12 win over lowly Citadel.

This has been a historically high-scoring series, according to the OddsShark College Football Database. The OVER is 10-4-1 over the last 15 meetings between these two ACC rivals and 3-0 in the last three games between these two teams.

Bettors will be quick to remember Florida State’s 51-14 road win over Clemson last year, but that was actually the first time that a game in this rivalry has been decided by more than 14 points since 2005. The loss should also serve as added motivation for the Tigers, who will want to exact some revenge and avoid getting embarrassed again.

Florida State isn’t likely to lose this year’s matchup outright at home, but Clemson should have enough fight to keep the score within three touchdowns.

Sports Odds, Lines And Betting News
6 Super Bowl 60 prop bet picks for Seahawks vs. Patriots6 Super Bowl 60 prop bet picks for Seahawks vs. Patriots
Sports Odds, Lines And Betting News

There are some fun prop bets on the board for Super Bowl 60

By Bill Williamson
NFL
What Super Bowl odds tell us about the final four teamsWhat Super Bowl odds tell us about the final four teams
NFL

The Seahawks head into the conference championships as the Super Bowl 60 favorite. We break down the odds of the final four teams.

By David Fucillo
NFL
Opening odds for 49ers-Seahawks in 2026 NFC Divisional roundOpening odds for 49ers-Seahawks in 2026 NFC Divisional round
NFL

The NFC Divisional round is set. We break down the opening odds for 49ers-Seahawks.

By Nick Simon
Sports Odds, Lines And Betting News
Opening odds for Rams-Bears in 2026 NFC Divisional roundOpening odds for Rams-Bears in 2026 NFC Divisional round
Sports Odds, Lines And Betting News

The NFC Divisional round is set. We break down the opening odds for Rams-Bears.

By Nick Simon
Women's College Basketball
3 women’s college basketball teams with enticing 2026 national championship odds3 women’s college basketball teams with enticing 2026 national championship odds
Women's College Basketball

UConn and South Carolina are the favorites, but other women’s college basketball teams have enticing title odds.

By Mitchell Northam
Men's College Basketball
March Madness odds: Chances for every team in the 2025 NCAA tournament to win the titleMarch Madness odds: Chances for every team in the 2025 NCAA tournament to win the title
Men's College Basketball

Cooper Flagg leads Duke to be the tournament favorite.

By James Dator and David Fucillo