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Come Fan with UsFriday, June 26, 2026

NFL odds 2016, Week 6: Brady, Patriots lead NFL betting favorites at the sportsbooks

The New England Patriots, Arizona Cardinals, and Green Bay Packers are among the betting favorites for Week 6 of the NFL betting slate.

Scott R. Galvin-USA TODAY Sports

The New England Patriots are 9-0 straight up and 7-2 against the spread in their last nine home games coming off a loss in their last game at home. The Patriots will try to avenge their home loss to Buffalo this Sunday when they host the Cincinnati Bengals.

New England is an 8.5-point favorite in Foxborough on the NFL lines at sportsbooks monitored by OddsShark.com. This will be just the second time since 2012 that the Bengals have been an underdog of a touchdown or more. Cincinnati is 9-5-1 ATS in its last 15 games as an underdog of seven points or more, but has gone just 2-10 SU in the last 12 instances.

The Patriots are 19-1 SU and 13-5-2 ATS in their last 20 home games played in October.

The Oakland Raiders have won each of their last three games and enter Week 6 tied for first place in the AFC West with the Denver Broncos at 4-1 SU. Oakland will face another division rival this Sunday, hosting the Kansas City Chiefs as a 1-point betting favorite.

Kansas City is 10-3 SU and ATS in its last 13 trips to Oakland. The OVER is 4-1 in the last five games between these two rivals.

NFL Week 6 Betting Lines (see the complete list at OddsShark)

Cincinnati at New England (-8.5)

New York Jets at Arizona (-7.5)

Dallas at Green Bay (-4.5)

Indianapolis at Houston (-3)

Kansas City at Oakland (-1)

Dak Prescott and Ezekiel Elliott have continued to thrive for the Dallas Cowboys, who are a perfect 4-0 SU and ATS over their last four games. The young duo will get their toughest test yet on Sunday, on the road against the Green Bay Packers.

Green Bay is 5-0 SU and 4-1 ATS in its last five games against the Cowboys per the OddsShark NFL Database. The Packers are a 4.5-point favorite at home for this contest.

And rounding out the Week 6 betting card, the Houston Texans are a 3-point favorite hosting the Indianapolis Colts for Sunday Night Football, and the Arizona Cardinals are a 7.5-point favorite at home against the New York Jets for Monday Night Football.

The Jets have been reeling over the last three weeks, going 0-3 SU and ATS with three straight double-digit losses. New York will try to get back on track against Arizona, a team the Jets have beaten five straight times.

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