Skip to main content
Come Fan with UsSunday, June 28, 2026

Red Sox vs. Giants 2016 odds: Boston set as road favorite in series opener at San Francisco

The Boston Red Sox have been pegged as betting favorites for the opener of a two-game series in San Francisco against the Giants on Tuesday.

Tommy Gilligan-USA TODAY Sports

The Boston Red Sox are 5-2 in interleague play so far this season with series wins over the Atlanta Braves and the Colorado Rockies. The Red Sox will look for more success against the National League in a two-game set in San Francisco against the Giants starting Tuesday.

Boston is a -120 betting favorite in Tuesday’s series opener at sportsbooks monitored by OddsShark.com. Rick Porcello will get the call for the Red Sox going up against Albert Suarez and the Giants, who would pay +100 on a home win.

The Red Sox have had the best offense in the majors this season by a considerable margin. Boston’s 5.89 runs per game of offensive production is half of a run higher than the second-place Cubs’ 5.40 runs per game.

With Xander Bogaerts, David Ortiz, Jackie Bradley Jr. and Dustin Pedroia all hitting over .300 this season, the Red Sox have the best batting average in baseball at .293. If the Red Sox continue to hit at this pace, they could come out on top of the American League despite a 4.73 ERA amongst their starters.

In Porcello’s last four road starts, the Red Sox are 0-4 per the OddsShark MLB Database. Porcello has a 5.84 ERA over that stretch.

The Giants have shaken off a mediocre 17-18 start to go 18-6 over their last 24 games, taking over first place in the division from the Los Angeles Dodgers in the process. Unfortunately for the Giants, the team lost its most productive bat last week when Hunter Pence suffered a hamstring injury that will keep the outfielder out of action for two months.

San Francisco is just 4-10 in its last 14 games against AL East opponents.

Tuesday’s total is set at eight runs at the sportsbooks. The UNDER is 7-4 in San Francisco’s last 11 games at home.

Despite being only two games long, this series should be an interesting one between two of the league’s top contenders behind the Chicago Cubs on the odds to win the World Series this season.

Wednesday’s game sets up as a potential pitcher’s duel with Boston’s David Price and San Francisco’s Madison Bumgarner projected to take the mound.

Sports Odds, Lines And Betting News
6 Super Bowl 60 prop bet picks for Seahawks vs. Patriots6 Super Bowl 60 prop bet picks for Seahawks vs. Patriots
Sports Odds, Lines And Betting News

There are some fun prop bets on the board for Super Bowl 60

By Bill Williamson
NFL
What Super Bowl odds tell us about the final four teamsWhat Super Bowl odds tell us about the final four teams
NFL

The Seahawks head into the conference championships as the Super Bowl 60 favorite. We break down the odds of the final four teams.

By David Fucillo
NFL
Opening odds for 49ers-Seahawks in 2026 NFC Divisional roundOpening odds for 49ers-Seahawks in 2026 NFC Divisional round
NFL

The NFC Divisional round is set. We break down the opening odds for 49ers-Seahawks.

By Nick Simon
Sports Odds, Lines And Betting News
Opening odds for Rams-Bears in 2026 NFC Divisional roundOpening odds for Rams-Bears in 2026 NFC Divisional round
Sports Odds, Lines And Betting News

The NFC Divisional round is set. We break down the opening odds for Rams-Bears.

By Nick Simon
Women's College Basketball
3 women’s college basketball teams with enticing 2026 national championship odds3 women’s college basketball teams with enticing 2026 national championship odds
Women's College Basketball

UConn and South Carolina are the favorites, but other women’s college basketball teams have enticing title odds.

By Mitchell Northam
Men's College Basketball
March Madness odds: Chances for every team in the 2025 NCAA tournament to win the titleMarch Madness odds: Chances for every team in the 2025 NCAA tournament to win the title
Men's College Basketball

Cooper Flagg leads Duke to be the tournament favorite.

By James Dator and David Fucillo