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Come Fan with UsFriday, June 26, 2026

NCAA tournament Sweet 16 odds: Gonzaga among the betting favorites for round

The Gonzaga Bulldogs are one of three No. 1 seeds still remaining at the NCAA Tournament and one of the betting favorites at the sportsbooks for the Sweet 16 this week.

NCAA Basketball: NCAA Tournament-Second Round-Gonzaga vs Northwestern
NCAA Basketball: NCAA Tournament-Second Round-Gonzaga vs Northwestern
Joe Camporeale-USA TODAY Sports

The Gonzaga Bulldogs are 3-0 straight up and against the spread in their last three games against the West Virginia Mountaineers. The Bulldogs will try to extend their winning streak against West Virginia to four games in the Sweet 16 Thursday.

Gonzaga is a 3-point betting favorite against the Mountaineers at sportsbooks monitored by OddsShark.com. At +3, the Mountaineers are the smallest of the three underdogs hoping to knock off a No. 1 seed in this round. The Bulldogs have fared well as a small favorite in recent seasons with a 5-0 SU record in their last five games as a favorite of three points or less.

With Villanova getting upset by No. 8 Wisconsin last weekend, only three No. 1 seeds remain at the NCAA Tournament. No. 1 Kansas is a 5-point favorite against Purdue on Thursday, and No. 1 North Carolina is a 7.5-point favorite facing Butler on Friday.

Villanova wasn’t the only top seed to fall in the Round of 32 as No. 2 Duke was knocked off by No. 7 South Carolina and No. 2 Louisville was bounced by No. 7 Michigan. No. 2 Arizona is a big favorite to advance to the Elite Eight going off at -7.5 against No. 11 Xavier on Thursday, but No. 2 Kentucky is expected to have a much tougher battle on its hands on Friday.

Kentucky is a 1-point underdog against the No. 3 UCLA Bruins. UCLA is 5-1 ATS in its last six games against Kentucky and 3-1 SU in its last four, including a 97-92 win as 11-point underdogs in Kentucky back in December. The Wildcats are 5-12 SU and 7-9-1 ATS in their last 17 games as a betting underdog per the OddsShark College Basketball Database.

The remaining three games on the board in the Sweet 16 also have razor-thin edges to the favorite, with No. 7 Michigan going off as a 1-point favorite against No. 3 Oregon on Thursday, No. 4 Florida at -2 facing No. 8 Wisconsin on Friday, and No. 3 Baylor favored by 3.5 points over No. 7 South Carolina on Friday

With the upset win over Duke, the Badgers improved to 5-1 SU and ATS over their last six games.

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