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Come Fan with UsTuesday, June 23, 2026

Loyola-Chicago vs. Michigan, Final Four odds: Ramblers underdogs facing the Wolverines

Loyola-Chicago will face its biggest challenge yet in this year’s March Madness in the form of a red-hot Michigan Wolverines team set as the favorite on the betting lines.

NCAA Basketball: NCAA Tournament-Second Round-Tennessee vs Loyola Chicago
NCAA Basketball: NCAA Tournament-Second Round-Tennessee vs Loyola Chicago
Matthew Emmons-USA TODAY Sports

The No. 11 Loyola Chicago Ramblers are 7-1 straight up and 8-0 against the spread in their last eight games as a betting underdog. This streak will be put to the test in this Saturday’s Final Four matchup against the No. 3 Michigan Wolverines.

Loyola-Chicago is a 5.5-point underdog at sportsbooks monitored by OddsShark.com. The Ramblers have been the betting underdog in all five of their NCAA tournament games this month.

Loyola-Chicago Ramblers vs. Michigan Wolverines

When: Saturday, March 31, 6:09 p.m. ET

Where: Alamodome, San Antonio

Betting Line / Total: Michigan -5.5 / 129.5 Points

Ramblers vs. Wolverines OddsShark Matchup Report

Loyola-Chicago Ramblers

The Ramblers scratched and clawed their way into the Elite Eight, beating Miami by two points before winning by only one point in two nail-biters against Tennessee and Nevada. But going up against the No. 9 Kansas State Wildcats as 1.5-point underdogs, Loyola-Chicago dominated the game from start to finish in a 78-62 rout.

Loyola-Chicago is the fourth No. 11 seed to advance into the Final Four and is hoping to be the first ever to advance to the championship game.

While the nation may see the Ramblers as a Cinderella team, this group has been making money for its backers all season. Loyola-Chicago is 21-1 SU and 18-4 ATS over its last 22 games including current runs of 14-0 SU and 6-0 ATS per the OddsShark College Basketball Database.

Michigan Wolverines

The Wolverines are riding a pretty impressive hot streak of their own going 13-0 SU and 10-3 ATS over their last 13 games. Michigan has proven its versatility throughout this NCAA tournament, showing off its potential on offense in a 99-72 win over Texas A&M in the Sweet 16 and following that up with a stout defensive performance in a 58-54 win over Florida State in the Elite Eight.

In two matchups against 11-seeds in March Madness since 2014, the Wolverines are 2-0 SU and 1-0-1 ATS.

Saturday’s total is set at 129.5 points. The OVER is 5-2 in Michigan’s last seven games played on a Saturday.

Loyola-Chicago is 0-7 SU and 1-6 ATS in its last seven games against Big Ten opponents. To make history as the lowest seed to ever advance into the NCAA tournament championship game, the Ramblers will need to break that streak and pull off their biggest upset of the postseason.

For more odds information, betting picks, and a breakdown of this week’s top sports betting news check out the OddsShark podcast with Jon Campbell and Andrew Avery. Subscribe on iTunes or listen to it at OddsShark.libsyn.com.

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