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Come Fan with UsTuesday, June 23, 2026

Dodgers vs. Giants 2018 odds: San Francisco home underdog for Friday series opener

Set as betting underdogs at the sportsbooks, the San Francisco Giants hope to continue their success at home over the Los Angeles Dodgers on Friday.

The San Francisco Giants are 10-5 on the moneyline in their last 15 home games against the Los Angeles Dodgers. The Giants will try to take advantage of their home crowd when they host their most hated rivals in a three-game series starting this Friday.

San Francisco is a +134 home underdog on the MLB odds on Friday at sportsbooks monitored by OddsShark.com. Derek Holland is expected to take the mound for the home team facing Kenta Maeda and the Dodgers (-144).

Los Angeles Dodgers at San Francisco Giants

When: Friday, April 6, 10:15 p.m. ET

Where: AT&T Park, San Francisco, California

Betting Line / Total: Los Angeles -144 / 8.5 Runs

Dodgers at Giants OddsShark Matchup Report

San Francisco Giants

When these two teams clashed in a season-opening series in Los Angeles, all four games ended in a shutout. San Francisco was on the right side of a pair of 1-0 shutout wins in the first two games of the series before dropping the last two games of the series 5-0 and 9-0.

After managing only two runs in four games against the Dodgers, San Francisco racked up 14 runs in a split two-game series against Seattle to move to 3-3 on the season. The Giants hope to carry that offensive momentum into this weekend’s series.

The Giants didn’t fare well as a home underdog last season with a 3-9 record in their last 12 games as one per the OddsShark MLB Database.

Los Angeles Dodgers

While it is far too early to push the panic button on the betting favorite to win the National League, the Dodgers haven’t looked much like a contender so far in 2018. Los Angeles got swept by the Arizona Diamondbacks this week to fall to 2-5 on the season and scored just one run in its last two games. With all-star third basemen Justin Turner on the shelf with a wrist injury, the Dodgers need to step up on offense to help their pitching staff out.

Friday’s total is set at 8.5 runs. The UNDER is 7-1 in the last eight games between the Dodgers and Giants.

The series continues this weekend with projected matchups of Rich Hill vs. Chris Stratton on Saturday and Clayton Kershaw vs. Ty Blach on Sunday. Blach out-dueled Kershaw in San Francisco’s 1-0 win on March 29 to help the Giants cash in as a +263 underdog.

For more odds information, betting picks and a breakdown of this week’s top sports betting news check out the OddsShark podcast with Jon Campbell and Andrew Avery. Subscribe on iTunes or listen to it at OddsShark.libsyn.com.

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