Skip to main content
Come Fan with UsMonday, June 22, 2026

Pirates vs. Cardinals 2018 odds: St. Louis clear home favorite on Tuesday betting lines

The St. Louis Cardinals host the Pittsburgh Pirates as they look to stay on track for a playoff spot, with the sportsbooks giving them the decided edge on the betting lines.

St Louis Cardinals v Los Angeles Dodgers
St Louis Cardinals v Los Angeles Dodgers
Photo by Harry How/Getty Images

The St. Louis Cardinals are 5-1 over their last six games and have won each of their last nine series overall. The Cardinals will go for a tenth straight series win in a three-game series this week against the Pittsburgh Pirates starting on Tuesday night.

St. Louis is a -155 home favorite on the MLB odds in the series opener at sportsbooks monitored by OddsShark.com. Jack Flaherty takes the mound for the home team facing Ivan Nova and the Pirates as +145 underdogs.

Pittsburgh Pirates at St. Louis Cardinals

When: Tuesday, August 28, 8:15 p.m. ET

Where: New Busch Stadium, St. Louis, Missouri

Betting Line / Total: St. Louis -155 / 8 Runs

Pirates at Cardinals OddsShark Matchup Report

St. Louis Cardinals

The Cardinals entered the month of August behind three teams in the NL Central and seemingly out of the playoff race with a record of 54-53. But with a 19-5 run over the team’s last 24 games, St. Louis has surged into second place in the division and first place in the Wild Card race.

Each of the team’s last 14 games have been won by two runs or more as the Cardinals have averaged 5.65 runs per game over their last 17 games, finally giving their excellent pitching staff the much-needed run support it wasn’t getting earlier in the year.

Jack Flaherty has been sensational in August with a 1.08 ERA, a 0.76 WHIP and 33 strikeouts in four starts this month. St. Louis is a perfect 4-0 in these four games.

Pittsburgh Pirates

The Pirates are going in the opposite direction. After coming into August slightly ahead of St. Louis in the standings with a 56-53 record, an 8-14 month has sent Pittsburgh tail-spinning out of the playoff race. Pittsburgh is just 1-7 in its last eight road games against St. Louis, according to the OddsShark MLB Database, and 3-14 in its last 17 road games against the Cardinals.

Tuesday night’s total is set at eight runs. The UNDER is 15-5 in the last 20 meetings between these two division rivals in St. Louis.

St. Louis enters this series with a 7-2 record in its last nine games against Pittsburgh. The series continues on Wednesday with a pitching matchup of Trevor Williams vs. Miles Mikolas and wraps up on Thursday night as Joe Musgrove squares off against John Gant.

For more odds information, betting picks and a breakdown of this week’s top sports betting news check out the OddsShark podcast with Jon Campbell and Andrew Avery. Subscribe on iTunes or listen to it at OddsShark.libsyn.com.

Sports Odds, Lines And Betting News
6 Super Bowl 60 prop bet picks for Seahawks vs. Patriots6 Super Bowl 60 prop bet picks for Seahawks vs. Patriots
Sports Odds, Lines And Betting News

There are some fun prop bets on the board for Super Bowl 60

By Bill Williamson
NFL
What Super Bowl odds tell us about the final four teamsWhat Super Bowl odds tell us about the final four teams
NFL

The Seahawks head into the conference championships as the Super Bowl 60 favorite. We break down the odds of the final four teams.

By David Fucillo
NFL
Opening odds for 49ers-Seahawks in 2026 NFC Divisional roundOpening odds for 49ers-Seahawks in 2026 NFC Divisional round
NFL

The NFC Divisional round is set. We break down the opening odds for 49ers-Seahawks.

By Nick Simon
Sports Odds, Lines And Betting News
Opening odds for Rams-Bears in 2026 NFC Divisional roundOpening odds for Rams-Bears in 2026 NFC Divisional round
Sports Odds, Lines And Betting News

The NFC Divisional round is set. We break down the opening odds for Rams-Bears.

By Nick Simon
Women's College Basketball
3 women’s college basketball teams with enticing 2026 national championship odds3 women’s college basketball teams with enticing 2026 national championship odds
Women's College Basketball

UConn and South Carolina are the favorites, but other women’s college basketball teams have enticing title odds.

By Mitchell Northam
Men's College Basketball
March Madness odds: Chances for every team in the 2025 NCAA tournament to win the titleMarch Madness odds: Chances for every team in the 2025 NCAA tournament to win the title
Men's College Basketball

Cooper Flagg leads Duke to be the tournament favorite.

By James Dator and David Fucillo