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Come Fan with UsSaturday, June 20, 2026

Athletics underdogs at Cardinals on Tuesday MLB odds

The Oakland Athletics visit the St. Louis Cardinals for an intriguing interleague series this week, with the A’s solid underdogs on the MLB odds for Tuesday night.

MLB: Game Two-Oakland Athletics at Texas Rangers
MLB: Game Two-Oakland Athletics at Texas Rangers
Ray Carlin-USA TODAY Sports

The Oakland Athletics are 5-2 in their last seven games overall and 5-2 in their last seven games against the St. Louis Cardinals as well. The Athletics hope to continue their success against the Cardinals in a two-game series against them that begins on Tuesday night.

Oakland is a +140 road underdog on the MLB odds for Tuesday’s series opener in St. Louis at sportsbooks monitored by OddsShark.com. Chris Bassitt is set to start for the Athletics going up against Jack Flaherty and the Cardinals as -150 home favorites.

Oakland Athletics at St. Louis Cardinals

When: Tuesday, June 25, 8:15 p.m. ET

Where: New Busch Stadium, St. Louis, Missouri

Betting Line / Total: St. Louis -150 / 9.0 Runs

Athletics at Cardinals OddsShark Matchup Report

Oakland Athletics Betting Notes

Year in and year out, the Athletics manage to roster a competitive baseball team despite having one of the lowest payrolls in baseball. Oakland ranks 26th in the MLB in payroll, but on the field the Athletics rank 12th in the majors in runs scored and 10th in team ERA at 4.22 through the squad’s first 79 games.

The A’s enter this matchup right in the thick of the wild card race in the American League with a record of 41-38.

The Athletics are 3-1 over their last four road games per the OddsShark MLB Database. Oakland is starting up a six-game road trip after playing its last 10 games at home.

St. Louis Cardinals Betting Notes

Less than three games separate the Chicago Cubs, Milwaukee Brewers and St. Louis in a tight race for the top spot in the National League Central.

The Cardinals rank ninth in the MLB in team ERA at 4.15, which has continued to help the team stay in the mix despite having on offense that ranks 19th in run production with 4.61 runs per game. St. Louis is just 3-6 in its last nine games with Jack Flaherty on the mound.

Athletics at Cardinals Betting Total

Tuesday night’s total is set at 9.0 runs. The UNDER is 4-1 in Oakland’s last five games on the road.

With both of these teams tied up in competitive playoff races, every game over this marathon of a regular season counts. Tanner Anderson is expected to make his fourth start of the season for the Athletics facing Adam Wainwright on Wednesday night. The A’s are 0-3 through Anderson’s first three starts with only eight total runs scored in those three games.

For more odds information, betting picks and a breakdown of this week’s top sports betting news check out the OddsShark podcast. Subscribe on iTunes or Spotify or listen to it at OddsShark.libsyn.com.

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