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Come Fan with UsSaturday, June 20, 2026

COLLEGE FOOTBALL GAMBLING: Week 10’s 20 best bets

This is our weekly college football gambling column. It’s called COLLEGE FOOTBALL GAMBLING.

A 13-9 Week 9 brings me to 77-77, -$750 as we enter Week 10. This week features fewer interesting games, but the money spends just the same if you pick winners. All wagers at -110 odds unless otherwise noted. Visit SB Nation odds partner Odds Shark for updated lines throughout each game week.

1. Florida State at Louisville Over 50.5: Louisville’s defense is rated No. 1 in almost every raw statistical category. It might be a tad overrated, though the health of Florida State’s right guard and right tackle are concerns against the excellent front. But FSU has scored at least 31 points in every game Jameis Winston has started, and Louisville’s offense is probably underrated, finally getting healthy for the first time this season.

2. Cincinnati at Tulane +4.5: Tulane has been playing very solid defense of late and should have a real shot to pull the upset at home against a high-scoring Cincinnati team.

3. Boston College at Virginia Tech -3: There is value on Virginia Tech after the somewhat deceiving margin by which the Hokies lost to Miami, due to multiple turnovers in the red zone. Boston College is one-dimensional, and the Hokies still have a shot to win the Coastal Division.

4. Auburn +1.5 at Ole Miss: Auburn could take advantage of Ole Miss’ defensive aggressiveness, and Auburn’s defensive front may be able to give Ole Miss’ banged-up offensive line some trouble.

5. Florida +13.5 v. Georgia: Georgia's defensive weakness is its secondary. And while I do not expect Florida to be able to exploit that, the Gators may be able to make this an ugly, defensive game and force Hutson Mason to make plays that he has yet to make.

6. Utah at Arizona State -5.5: Arizona State's offense was stopped somewhat in Week 9 due to the incredible windstorm in Washington, but I expect the Sun Devils to have the tempo cranked up in the desert. The loss of receiver Dres Anderson for Utah is an important one. Three consecutive single-score wins have made Utah a bit overrated on the Vegas line.

7. Arizona at UCLA -6.5: Arizona’s defense continues to be a liability, and Arizona’s 4-1 record in single-score games has created value in betting against them when the opportunity presents itself.

8. Duke at Pitt -3: Duke excels at beating sloppy teams. Pitt was extremely sloppy, fumbling six times against Georgia Tech last weekend, but on the year the Panthers have not been that sloppy. The margin of the loss to Georgia Tech may be creating value on Pitt.

9. North Carolina +15 at Miami: The Hurricanes are now without their top three offensive tackles, which means some major reshuffling. North Carolina’s defense is not good, but the Miami offensive line situation could be enough to stop the Hurricanes a few times and keep the Tar Heels in the game.

10. Colorado State at San Jose State +7: San Jose State’s passing defense is very good relative to its competition (the loss to Navy aside), and that should be enough to keep it close against a good passing offense.

11. Utah State at Hawaii Under 42.5: Utah State has some major quarterback issues, and Hawaii’s offense is a mess.

12. East Carolina at Temple +8: Temple has the ability to play very solid defense. And the weather in the Northeast could be nasty this weekend and not conducive to throwing the football, ECU’s preferred method of offense.

13. Indiana at Michigan -6.5: Sure, Michigan was dominated by Michigan State, but Indiana’s freshman QB Zander Diamont has thrown 15 passes for 11 yards in his career.

14. Arkansas at Mississippi State -10: Mississippi State’s weakness is its secondary, but Arkansas does not throw the football especially well. And surprisingly for this time of year, the Bulldogs do not have a big game next week, so there’s no look-ahead scenario.

15. Notre Dame v. Navy +14.5: Notre Dame has fallen victim to a lookahead scenario already this year, when it struggled with North Carolina before Florida State. Now it has Navy in an NFL stadium before traveling to face Arizona State.

16. Maryland +4 at Penn State: Wisconsin did dominate Maryland in Week 9, but Penn State’s offense can’t possibly hope to duplicate what Wisconsin did. I’m taking the points in what should be a close game.

17. Purdue at Nebraska -23.5: Purdue's defense is not equipped to stop Ameer Abdullah, and there is no potential lookahead spot for the Cornhuskers.

18. Tennessee at South Carolina -7 (+100): Tennessee has one of the worst offenses in the major conferences, and while South Carolina’s defense is plenty suspect, it should get enough stops at home for the Gamecocks’ solid offense to pull away.

19. Oklahoma State at Kansas State -14: Kansas State is going to force Oklahoma State QB Daxx Garman to throw the football accurately underneath, and so far, he has not been able to do so in relief of the injured J.W. Walsh.

20. Washington -4 at Colorado: The Huskies play solid defense, and the offensive performance last week was partially attributable to the absence of QB Cyler Miles and the crazy windstorm during the game against Arizona State.

What bets do you like this week? Let us know in the comment section.

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