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Come Fan with UsWednesday, June 24, 2026

COLLEGE FOOTBALL GAMBLING: Week 7’s 21 best bets, starring Big 12 defenses

Welcome back to our college football gambling column. It’s called COLLEGE FOOTBALL GAMBLING.

Troy Taormina-USA TODAY Sports

A 14-10 mark in Week 6 brings me to 52-45, $250 as we enter Week 7. This week features a ton of big games. All wagers at -110 odds unless otherwise noted. Visit SB Nation odds partner Odds Shark for updated lines throughout each game week.

Editor’s note: a previous version of this article incorrectly listed Indiana as a favorite. The Hoosiers are an underdog.

1. Oregon at UCLA +3: Neither offensive line is good, but at least UCLA’s is healthy. And UCLA’s defense is a lot better.

2. TCU at Baylor Under 66.5: I still believe in TCU’s defense more than I do its offense, and Baylor’s defense is pretty good. Meanwhile, Baylor quarterback Bryce Petty hasn’t looked right this year.

3. Texas at Oklahoma Under 47: Texas plays good defense, and its offense is terrible. It will try to make this into an ugly game.

4. USC at Arizona Over 68: Late-night game. Both teams like to use tempo, and neither defense is all that good. Points!

5 and 6. Penn State at Michigan -1 AND Under 41.5 points: Michigan covered last week against Rutgers, and its defense continues to keep this team in games. Perhaps the offense will figure it out this week? Penn State is really struggling to score points as well, and has a good defense of its own.

7. Ole Miss at Texas A&M -2: A&M dropped a ton of balls and had some bad turnovers in losing at Mississippi State. This is a huge hangover for Ole Miss.

8. Georgia at Missouri +3: Missouri has stopped the run against most offenses this year, and it rushes the passer very well. Georgia’s secondary is poor. Mizzou is also coming off a bye week.

9. LSU at Florida Under 47.5: Gators quarterback Jeff Driskel ranks No. 97 nationally in passer rating against power-conference competition. LSU, on the other hand, has converted two of 26 third downs in conference play. TWO!

10. BYU at UCF -3: The loss of quarterback Taysom Hill and other injured players will devastate BYU, and UCF plays pretty good defense.

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11. Indiana +3 at Iowa: Up-tempo running game from the Hoosiers gets it done in a sleepy noon game.

12. Duke +4 at Georgia Tech: Duke gets a bye week before playing a flexbone team. Georgia Tech has been bad under Paul Johnson when opponents get extra prep time for its unique offense.

13. Northwestern at Minnesota -4: Northwestern went from underrated to overrated quite quickly. Look for Minnesota to pound them with the ground game.

14. Louisiana Monroe +21.5 at Kentucky: Kentucky is coming off its biggest win in years and has LSU on deck. The focus probably won’t be there against the Warhawks.

15. FIU at Texas San Antonio -12: FIU has been the beneficiary of a ridiculous plus-nine turnover margin the last two weeks. It should end this weekend.

16. Idaho +22.5 at Georgia Southern: Southern has been a covering machine, but last week it was the beneficiary of some ridiculous turnovers.

17. Houston +9 at Memphis: I’ve been on Memphis all season, but this feels too inflated for a team that is simply not playing great defense right now.

18. Miami (Ohio) at Akron -14: Miami has a horrible defense, and Akron can get enough stops to open up a big lead.

19. Colorado State -1.5 at Nevada: Jim McElwain is an excellent coach, and I look for the Rams to run the ball all over the Wolf Pack.

20. Toledo +3 at Iowa State: Some fear here that Toledo running back Kareem Hunt is hurt, but Toledo has a good team, not just a good back.

21. North Texas at UAB -6: The Blazers scored three turnovers last weekend to win at Western Kenucky, and that shouldn’t happen quite so much this weekend.

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