Betting lines, according to lines tracked by OddsShark, are out for week two, and while the week is full of mismatches, there are a few big games with interesting spreads. Most notably, Oklahoma opened as a three-point favorite at upstart Tennessee in what amounts to the biggest non-conference game of the past half-decade for the Volunteers. However, the line has already been bet down to a -1 just a few hours after it opened.
Oklahoma a road favorite at Tennessee, and Week 2’s other early betting lines
Vegas expects close fights in Oklahoma-Tennessee and Oregon-Michigan State.
Kevin Jairaj-USA TODAY Sports
The other big games of the week have already seen movement. Michigan State is now a two-point favorite at home against Oregon after that game opened as a pick em, while Mississippi State is now just a two-point underdog at home to LSU after the game opened at a three-point spread.
On the other end of the spectrum, there are some massive spreads, as college football’s best take on weaker opponents. USC is a massive 43.5-point favorite over Idaho, while Ohio State, Alabama and Wisconsin are all favorites of at least 33 points.
| Game | Favorite | Opening Line |
| Idaho at USC | USC | 43.5 |
| Hawaii at Ohio State | Ohio State | 38 |
| Middle Tennessee at Alabama | Alabama | 34 |
| Miami (Ohio) at Wisconsin | Wisconsin | 33 |
| South Florida at Florida State | Florida State | 29 |
| UCLA at UNLV | UCLA | 28 |
| South Alabama at Nebraska | Nebraska | 27 |
| Tulane at Georgia Tech | Georgia Tech | 26 |
| Ball State at Texas A&M | Texas A&M | 26 |
| Fresno State at Ole Miss | Ole Miss | 23 |
| Kansas State at UTSA | Kansas State | 22.5 |
| Appalachian State at Clemson | Clemson | 21 |
| Toledo at Arkansas | Arkansas | 21 |
| Georgia at Vanderbilt | Georgia | 17 |
| Miami at Florida Atlantic | Miami | 16.5 |
| Buffalo at Penn State | Penn State | 16.5 |
| UTEP at Texas Tech | Texas Tech | 16.5 |
| UMass at Colorado | Colorado | 16 |
| Rice at Texas | Texas | 16 |
| Central Florida at Stanford | Stanford | 16 |
| Oregon State at Michigan | Michigan | 14 |
| East Carolina at Florida | Florida | 13 |
| Missouri at Arkansas State | Missouri | 13 |
| Houston at Louisville | Louisville | 12.5 |
| Notre Dame at Virginia | Notre Dame | 11.5 |
| Pitt at Akron | Pitt | 11.5 |
| Utah State at Utah | Utah | 11 |
| Eastern Michigan at Wyoming | Wyoming | 11 |
| Memphis at Kansas | Memphis | 10.5 |
| Arizona at Nevada | Arizona | 10.5 |
| Bowling Green at Maryland | Maryland | 10 |
| San Diego State at Cal | Cal | 9 |
| Kentucky at South Carolina | South Carolina | 7.5 |
| FIU at Indiana | Indiana | 7.5 |
| San Jose State at Air Force | Air Force | 7 |
| Army at UConn | UConn | 6.5 |
| Temple at Cincinnati | Cincinnati | 6.5 |
| Wake Forest at Syracuse | Syracuse | 5.5 |
| Washington State at Rutgers | Rutgers | 5.5 |
| Georgia State at New Mexico State | New Mexico State | 5.5 |
| Minnesota at Colorado State | Minnesota | 5 |
| Western Michigan at Georgia Southern | Western Michigan | 4.5 |
| Iowa at Iowa State | Iowa | 4 |
| Marshall at Ohio | Marshall | 4 |
| Louisiana Tech at Western Kentucky | Western Kentucky | 3 |
| Oklahoma at Tennessee | Oklahoma | 3 |
| Tulsa at New Mexico | New Mexico | 3 |
| LSU at Mississippi State | LSU | 3 |
| North Texas at SMU | Even | Even |
| Oregon at Michigan State | Even | Even |
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