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Come Fan with UsMonday, June 22, 2026

C.J. Spiller injury update: Bills RB practices Friday, available for fantasy owners

C.J. Spiller practiced again on Friday and will play in Week 7. We break down the fantasy implications.

Jason Miller

Buffalo Bills running back C.J. Spiller (ankle) got a full practice in with the team on Friday. Spiller is expected to play in Sunday's game against the Miami Dolphins. He has been dealing with the ankle injury for the last couple weeks and is still not 100 percent healthy.

Fantasy Impact: Even though Spiller will suit up against the Dolphins, the size of his workload is very much in question. With Fred Jackson playing at a high level and Tashard Choice also in the mix, Spiller presents a somewhat risky fantasy play, even against a Dolphins defense that gives up the second-most points in the league to running backs. The 32-year-old Jackson is averaging 4.6 yards per carry and has four touchdowns on the season. It wouldn't make much sense for the Bills to overwork their star running back and his ankle when Jackson has been so productive.

The uncertain workload for Spiller makes him a mediocre RB2 option at best this week. While Spiller absolutely oozes upside, it is safe to say that he has not lived up to his top-five ADP in 2013. He has averaged 4.2 per carry with only one touchdown and one 100-yard game this year.

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