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Come Fan with UsTuesday, June 23, 2026

Matt Barkley took advantage of a depleted Colorado secondary, throwing a school record six touchdown passes in a 42-17 win.

  • Brian Floyd

    Brian Floyd

    USC Vs. Colorado Final Score: Matt Barkley Sets Record In 42-17 Win

    USC quarterback Matt Barkley set a school record for touchdown passes in a game on Friday night as the Trojans rolled to a 42-17 win over the Colorado Buffaloes. Colorado actually struck first, riding the momentum of a Friday night game in Boulder and a new uniform wrinkle -- the Buffaloes changed into black helmets just before the game. But it was all USC from there as the Trojans hit the throttle and Barkley throttled a depleted Colorado secondary.

    Barkley threw for 326 yards and a school record six touchdown passes while also throwing an interception. Curtis McNeal rushed for a team-high 85 yards, with Amir Carlisle adding 62 yards. Robert Woods and Marquis Lee had nearly the same game, with the former picking up 132 receiving yards and two touchdowns and the latter finishing with 131 yards and two touchdowns.

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  • Sean Keeley

    Sean Keeley

    USC Vs. Colorado Game Time, TV Schedule, Spread And More

    The Trojans are currently installed as 21.5 to 22 point favorites (depending on which sportsbook you look at) against Colorado. It looks like Vegas doesn’t see an emotional hangover in the Trojans future in what could easily be a trap game.

    This is the first-ever meeting within the Pac-12 between USC and Colorado. But USC is 5-0 all-time against the Buffaloes, with their last game played in 2002.

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