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Come Fan with UsTuesday, June 23, 2026

USC Vs. Colorado Game Time, TV Schedule, Spread And More

This is the first-ever meeting within the Pac-12 between USC and Colorado. But USC is 5-0 all-time against the Buffaloes, with their last game played in 2002.

The USC Trojans are coming off an emotionally draining 56-48 loss to the Stanford Cardinal last Saturday. In what is being dubbed the ‘game of the year' in the college football, the Trojans fought one of the top teams in the country and their Heisman hopeful quarterback through three overtimes before finally falling in defeat. According to the sportsbooks, USC doesn't have quite the same task ahead of them as they face the Colorado Buffaloes.

The Trojans are currently installed as 21.5 to 22 point favorites (depending on which sportsbook you look at) against Colorado. It looks like Vegas doesn’t see an emotional hangover in the Trojans future in what could easily be a trap game.

This is the first-ever meeting within the Pac-12 between USC and Colorado. But USC is 5-0 all-time against the Buffaloes, with their last game played in 2002.

Game date, time: 9:00 pm ET, Friday, November 4th, 2011

Location: Boulder, Colorado

TV channel: ESPN

Spread: USC favored by 22

Series history: USC leads series, 5-0

For further reading, news, discussion and more, visit USC blog Conquest Chronicles and Colorado blog The Ralphie Report. Here’s this week’s college football TV schedule, and stay tuned to SB Nation’s college football news hub for more.

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