Best DFS picks for Eagles at Packers in Week 10

Week 10 of the 2025 NFL season wraps up tonight with a big-time NFC showdown featuring the Philadelphia Eagles visiting the Green Bay Packers. Green Bay enters as a 1.5-point home favorite, with an over/under of 45.5. The Eagles are looking to hit the ground running after their bye last week while the Packers will try to maintain their lead atop a competitive NFC North race.

Below, we will take a look at the best DFS plays for this Monday night showdown.

Jacobs has been an excellent add in DFS through the first half of the season and he’s rewarded managers with an average of 18.2 fantasy points per game. This can be mainly attributed to the veteran All-Pro being a touchdown machine for the Packers this season, as his 10 trips to the end zone is second in the NFL behind Jonathan Taylor. He also has four games where he’s hauled in at least four targets in the passing game, making him a central piece of the Packers’ attack.

Tonight, he’ll be going up an Eagles defense that hasn’t exactly been world beaters against the run. Opposing running backs have been averaging 21.3 fantasy points per game against the Philly D, a unit that currently ranks 24th in rushing defensive DVOA. It would not be a surprise to see him find the end zone a few times this evening and he’s definitely worthy of a captain’s spot.

After missing their Week 8 matchup against the Giants with a hamstring injury, Brown has had extra time to rest up and will be back in action for the Eagles tonight. The early-season concerns over his involvement in the passing game seems to have been quelled (for now) as he began to heat up prior to the injury, last seen toasting the Vikings for 121 yards and two touchdowns in Week 7.

Brown has averaged 8.3 targets over his last six outings and I’d expect Jalen Hurts to continue to hunt for his top receiver option early and often in this primetime matchup. Even if he doesn’t score tonight, managers who select him as the captain of their lineups should be satisfied.

Goedert enters tonight’s matchup leading all tight ends in touchdowns with seven on the season and that has allowed him to be a strong fantasy option even though he ranks 18th in receiving yards in his position. The veteran has been the most efficient red-zone tight end target in the NFL so far, catching all seven of his targets for 39 yards with six of his TD’s coming inside of the 20.

If the Eagles get close to paydirt, you can bank on Goedert getting a look and the potential of him scoring makes him a captain-worthy add with some value for tonight.

Green Bay suffered a devastating blow last week with tight end Tucker Kraft suffering a season-ending ACL tear in their loss to the Panthers. Enter Musgrave, who caught a season-high three receptions for 34 yards in the setback. The third-year player will now step in as the Packers’ TE1 for the rest of the season and while it’s unlikely that he’ll have the same production as Kraft, he should get enough looks to make him a worthwhile Flex option.

Bigsby was explosive in the Eagles’ win over the Giants two weeks ago, taking nine carries for 104 yards in the victory. It was his first taste of action since being traded from Jacksonville to Philly at the start of the year and his teammates weren’t surprised by his performance. The Eagles would still be smart to manage Saquon Barkley’s workload as they enter the second half of the season and Bigsby could solidify himself as a strong backup option tonight.

Wilson has been an effective backup to Jacobs this season and had his best performance of the season against the Steelers a few weeks ago, racking up 61 rushing yards and 26 receiving yards. Considering some of the Eagles’ vulnerabilities against the run, there’s a chance that the third-year back could put up some respectable numbers on the ground this evening.