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Come Fan with UsSunday, June 21, 2026

NFL Odds And Lines Week 8: Browns Vs. 49ers

The San Francisco 49ers are 9-1/2 point favorites over the Cleveland Browns on Sunday. The 49ers should be able to cover that and move to 6-1.

The San Francisco 49ers hold want appears to be an insurmountable lead over the rest of the NFC West and they'll look to extend that on Sunday when they host the Cleveland Browns. The 5-1 49ers are one of the more surprising teams this season and maybe it is a result of new coach Jim Harbaugh. But it shouldn't be surprising that the 49ers opened as 9-1/2 point favorites over the Browns, according to Odds Shark.

The Browns, on the other hand, have been a mild disappointment with their 3-3 record. If Peyton Hillis is able to play, that will be a huge plus for the team, but he alone won't bring victory. Colt McCoy hasn't had the season many expected, throwing eight touchdowns to four interceptions. The over/under is at 38-1/2 points and the score could go over that.

Be sure to visit Odds Shark for more NFL Week 8 odds and lines. For more on this game, check out our Browns blog Dawgs by Nature and our 49ers blog Niners Nation. And head over to SB Nation NFL for more on Week 8.

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