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Come Fan with UsThursday, June 25, 2026

Week 15 NFL picks: Lions vs. Cardinals

Most experts feel Detroit will cruise to a win over Arizona this weekend.

Jeff Hanisch-USA TODAY Sports

Week 15 will bring together two teams that have underachieved in 2012. For the Lions, they've really struggled to close out games in the fourth quarter, and it's led them to a 4-9 record. As for the Cardinals, they began the year with four straight wins just to drop their last nine contests.

As the experts begin making their predictions for this weekend, just about everyone figures the Lions will have their way on the field.

According to ESPN’s pundits, it’s unanimous, as all 12 picked Detroit to win. ESPN’s computer simulation of the game also has the Lions winning, as do their viewers in the fan vote.

All of CBS Sports’ experts have made their picks against the spread. With the Lions favored by 6½ points, just one person, Josh Katzowitz, sees Arizona beating the spread.

As for FOX Sports, all four of their gurus see the Lions winning, although John Halpin believes Detroit will be unable to cover the spread.

Kickoff between the Cardinals and Lions is scheduled for 4:05 p.m. ET on Sunday, Dec. 16.

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