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Come Fan with UsSaturday, June 20, 2026

Week 2 NFL Odds: Cardinals Vs. Patriots

The New England Patriots are favored by 15.5 points against the Arizona Cardinals, according to OddsShark. The Patriots are 5-0 straight up in their last five games against the Cardinals.

Sep 09, 2012; Nashville, TN, USA; New England Patriots quarterback Tom Brady (12) drops back to hand off against the Tennessee Titans during the second half at LP Field. The Patriots beat the Titans 34-13. Mandatory credit: Don McPeak-US PRESSWIRE
Sep 09, 2012; Nashville, TN, USA; New England Patriots quarterback Tom Brady (12) drops back to hand off against the Tennessee Titans during the second half at LP Field. The Patriots beat the Titans 34-13. Mandatory credit: Don McPeak-US PRESSWIRE
Sep 09, 2012; Nashville, TN, USA; New England Patriots quarterback Tom Brady (12) drops back to hand off against the Tennessee Titans during the second half at LP Field. The Patriots beat the Titans 34-13. Mandatory credit: Don McPeak-US PRESSWIRE

The New England Patriots have been listed as 15.5-point favorites as they face off against the Arizona Cardinals this Sunday at Gillette Stadium. According to OddsShark, the over/under for the game has been set at 48.

New England is coming off an impressive 34-13 victory over the Tennessee Titans. The Patriots looked typically impressive on the offensive side of the ball, and got some solid contributions from rookies Dont'a Hightower and Chandler Jones on the defensive side. Tom Brady took a shot on the nose during the opener, but it's unlikely to be a factor this weekend.

Arizona opened its season with a victory as well, defeating the Seattle Seahawks, 20-16. Arizona starting quarterback John Skelton had to be carted off the field with an ankle issue, and it looks as if he'll be out for the next several weeks. Kevin Kolb did well filling in for Skelton in the opener, and he will be called upon to do so again against the Patriots. Kolb could use some more help from the Cardinals' rushing attack, as they managed just 43 yards total on the ground against Seattle.

The game is scheduled to kick off at 1 p.m. ET, and coverage from Gillette Stadium will be carried on FOX.

For more on the Patriots, make sure to check out Pats Pulpit. For more on the Cardinals, visit Revenge of the Birds.

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