The Patriots are the week’s biggest favorites. Check out all the NFL Week 2 odds here.
Detroit Lions Vs San Francisco 49ers: Betting Odds, Preview and Pick


June 12, 2012; Santa Clara, CA, USA; San Francisco 49ers quarterback Alex Smith (11) drops back to throw a pass during 49ers minicamp at San Francisco 49ers training facility. Mandatory Credit: Ed Szczepanski-US PRESSWIRE Detroit has visited San Francisco 10 times since 1981 and they have lost 10 times.
In those 10 games, the UNDER bet has been a winner for totals bettors nine times (one game was a push).
Read Article >New York Jets Vs Pittsburgh Steelers: Betting Odds, Preview and Prediction


September 9 2012; Denver, CO, USA;Pittsburgh Steelers quarterback Ben Roethlisberger (7) looks to pass during the first quarter against the Denver Broncos at Sports Authority Field. Mandatory Credit: Ron Chenoy-US PRESSWIRE The Jets are 1-6 SU in seven trips here since 1981 and get plenty of respect from oddsmakers after their big win last week. The Steelers stumbled a week ago and the opening line has actually been bet down to -4.5 at one shop tracked by OddsShark.com (the lines provider to SBNation),
Safety Troy Polamalu and linebacker James Harrison did not practice on Friday and are questionable for Sunday.
Read Article >Washington Redskins Vs St. Louis Rams: Betting Odds, Preview and NFL Pick

PresswireThe Rams have been a disaster at home in September games dating back many years. They are just 2-11 ATS in their past 13 at home during September.
But the Redskins, despite their Week 1 success, have not been a great bet as a favorite. In 12 recent games in that role, they have covered the spread just twice, according to the OddsShark.com Twitter feed.
Read Article >Oakland Raiders Vs Miami Dolphins: Betting Odds, Preview and Prediction

PresswireIf the amount of betting on this game is any indication, fans either don’t care much about the game or don’t trust either team with the Week 2 point spread.
“It’s the lowest-bet game volume-wise of the week so far, so fans are unaccustomed to the Raiders as road chalk and uncomfortable with the Dolphins, period,” said Bovada spokesman Kevin Bradley.
Read Article >Tampa Bay Buccaneers Vs New York Giants: Betting Odds, Preview and Prediction


EAST RUTHERFORD NJ - OCTOBER 17: Eli Manning #10 of the New York Giants against the Detroit Lions at New Meadowlands Stadium on October 17 2010 in East Rutherford New Jersey. (Photo by Nick Laham/Getty Images) *** Local Caption *** Eli Manning Getty ImagesThere are no guarantees in betting NFL games, but there is one bet that has been perfect 12 times since 1981.
”The point spread is not always the betting odds of choice when you are handicapping a game and that angle is proof,” said Jeff Grant of SportsbookReview.
Read Article >Kansas City Chiefs Vs Buffalo Bills: Betting Odds, Preview and Pick


ORCHARD PARK, NY - SEPTEMBER 18: Ryan Fitzpatrick #14 of the Buffalo Bills looks to handoff to Fred Jackson #22 of the Buffalo Bills at Ralph Wilson Stadium on September 18, 2011 in Orchard Park, New York. (Photo by Rick Stewart/Getty Images) Getty ImagesAnd one of the most one-sided head-to-head trends in all of football is on play here as the Bills are 10-2 ATS in 12 games against KC since 1994, according to the Week 2 NFL trends list.
The Bills were holding steady as a 3-point home favorite at shops such as Top Bet. About 63 percent of the point spread wagering was on the Chiefs as of Friday, according to the NFL consensus data at OddsShark.com.
Read Article >New Orleans Saints Vs Carolina Panthers: Betting Odds, Preview and Prediction

Getty ImagesAnd they do so against a team they have dominated on the road (7-3 ATS past 10 trips to Carolina) and as 3-point road favorites, according to the NFL odds menu at OddsShark.com.
“Carolina is a rising team, but they have been horrible in the underdog, losing 18 of 19 SU over the past few seasons,” said Jack Randall of OddsShark.com, provider of lines to SBNation.
Read Article >Houston Texans Vs Jacksonville Jaguars: Betting Odds, Preview and Prediction


Aug 11, 2012; Charlotte, NC, USA Houston Texans running back Arian Foster (23) runs the ball during the first quarter against the Carolina Panthers at Bank of America Stadium. Mandatory Credit: Jeremy Brevard-US PRESSWIRE Houston was a 7-point road favorite and had been bet up to -7.5 and -8 at various online shops.
There isn’t much to dislike about the Houston Texans. Last year the defense quietly developed into one of the best in the league, and offensively you have three of the best players at their respective positions in quarterback Matt Schaub, running back Arian Foster and wideout Andre Johnson.
Read Article >NFL Picks Week 2: These Predictions Can’t Be Wrong!

Getty ImagesWeek 2 in the NFL gets started with the Chicago Bears and Green Bay Packers on the first edition of Thursday Night Football of the year. That isn’t the only big game of the week though -- the Jets visit the Steelers, the Eagles host the Ravens and the Falcons and Broncos will meet on Monday Night Football. Below, we attempt to accurately predict those, and every NFL game this week.
What a Thursday night opener. This is one of the best games of the year with two teams that have plans to make a deep playoff run. The Packers lost last week and I can’t imagine them going 0-2 on the season. Aaron Rodgers is too good, with or without Greg Jennings.
Read Article >Baltimore Ravens Vs Philadelphia Eagles: Betting Odds, Preview and Pick

Getty ImagesPhiladelphia was a 1-point home favorite at midweek because the Ravens were the only team in this matchup that looked like a contender in Week 1.
The Eagles struggled to a weak win at Cleveland while the Ravens routed Cincinnati. And Baltimore’s recent history against the NFC East generally and the Eagles specifically is giving bettors more ammunition to bet on the Ravens.
Read Article >Week 2 NFL Odds: Lions Vs. 49ers

Getty ImagesKickoff is scheduled for Sunday night at 8:20 p.m. ET from Candlestick Park, and the game can be seen on NBC.
For more on the Lions, check out Pride Of Detroit. For more on the 49ers, please make sure to visit Niners Nation.
Read Article >Week 2 NFL Odds: Titans Vs. Chargers

Getty ImagesThe game is scheduled to kick off Sunday at 4:25 p.m. ET from Qualcomm Stadium, and can be seen on CBS.
For more on the Chargers, please visit Bolts from the Blue. For more on the Titans, check out Music City Miracles.
Read Article >Week 2 NFL Odds: Vikings Vs. Colts

Getty ImagesKickoff is scheduled for 1 p.m. ET, and the game will be carried on FOX.
For more on the Vikings, please visit Daily Norseman. For more on the Colts, check out Stampede Blue.
Read Article >Week 2 NFL Odds: Redskins Vs. Rams

PresswireFor more coverage of the Rams, check out Turf Show Times, while Hogs Haven has all the latest news and notes on the Redskins.
Read Article >Week 2 NFL Odds: Saints Vs. Panthers

PresswireOddsmakers opened up the Saints as 6.5-point favorites. Bettors obviously were not so impressed with New Orleans’ opening performance, as the Saints are now favored at most sites by only 2.5 to 3 points.
The over-under sits at 51. In New Orleans’ last five games, the total has gone over every time, but eight of the last nine Saints-Panthers games in Charlotte have come in under the total. In the last 10 games between the two teams, New Orleans is 6-4 straight up, but the Panthers are 7-3 against in those same games.
Read Article >Week 2 NFL Odds: Cowboys Vs. Seahawks

Getty ImagesAccording to the latest odds from OddsShark.com, Dallas is a 3-point favorite over Seattle with an over/under of 41.5.
For more coverage of the Cowboys, check out SB Nation Dallas as well as Blogging The Boys, while SB Nation Seattle and Field Gulls have all the latest on the Seahawks.
Read Article >Week 2 NFL Odds: Cardinals Vs. Patriots


Sep 09, 2012; Nashville, TN, USA; New England Patriots quarterback Tom Brady (12) drops back to hand off against the Tennessee Titans during the second half at LP Field. The Patriots beat the Titans 34-13. Mandatory credit: Don McPeak-US PRESSWIRE The game is scheduled to kick off at 1 p.m. ET, and coverage from Gillette Stadium will be carried on FOX.
For more on the Patriots, make sure to check out Pats Pulpit. For more on the Cardinals, visit Revenge of the Birds.
Read Article >Week 2 NFL Odds: Chiefs Vs. Bills


EAST RUTHERFORD, NJ - SEPTEMBER 09: C.J. Spiller #28 of the Buffalo Bills runs against the New York Jets during their season opener at MetLife Stadium on September 9, 2012 in East Rutherford, New Jersey. (Photo by Jeff Zelevansky/Getty Images) Getty ImagesCheck out all the NFL Week 2 odds at OddsShark. There’s more NFL news at our SB Nation NFL hub. Be sure to check us out on YouTube:
Already getting shelled in your fantasy league and want a new challenge? Try our Pick 6 challenge and compete against other SB Nation readers!
Read Article >Week 2 NFL Odds: Ravens Vs. Eagles


Sep 9, 2012; Cleveland, OH, USA; Philadelphia Eagles quarterback Michael Vick (7) makes a pass during the second half at Cleveland Browns Stadium. Mandatory Credit: Raj Mehta-US PRESSWIRE Oddsmakers opened up the Eagles as 1-point favorites, at home. Lines are fluctuating between favoring the home team by a point to giving them 2.5. Baltimore is 4-1 straight up in its last five games; Philadelphia is 5-0 straight up in its last five games, but only 3-8 straight up in its last 11 games at home, and 3-6 against the spread in its last nine home contests.
The over-under opened at 43.5 and has bumped up to 46 at most shops. Both teams feature impressive defenses and potentially explosive offenses -- bettors should note that the total has gone under in six of Baltimore’s last nine games, and in four of Philadelphia’s last five.
Read Article >Week 2 NFL Odds: Texans Vs. Jaguars


Sep 9, 2012; Houston, TX, USA; Houston Texans safety Glover Quin (29) chest bumps Texans mascot Toro before the game against the Miami Dolphins at Reliant Stadium. Mandatory Credit: Kirby Lee/Image of Sport-US PRESSWIRE OddShark’s Week 2 odds preview lists trends for each Week 2 matchup. It’s noted that Houston has gone 9-4 straight-up in its last 13 games while the total has gone over for Jacksonville in five of its last six games.
Five Dimes lists the Texans as 9-point favorites, while Bovada, SportsBook.com and Top Bet all have the Texans favored by 7.5 points. The over/under is set around 41.
Read Article >Week 2 NFL Odds: Browns Vs. Bengals

Getty ImagesFor more on the Bengals, be sure to visit Cincy Jungle. To read more about the Browns, check out Dawgs By Nature.
Read Article >Week 2 NFL Odds: Raiders Vs. Dolphins

Getty ImagesFive Dimes, SportsBook.com and Top Bet all list Oakland as 2.5-point favorites with the over/under set around 38.
The game from Sun Life Stadium in Miami is a 1 p.m. ET kickoff, 10 a.m. for Oakland fans.
Read Article >Week 2 NFL Odds: Bears Vs. Packers

Getty ImagesAfter opening as 4-point favorites, the point spreads have swelled in the Packers’ favor and are now at 6 points on most sites, even 7 on others. Although, considering the gap in the quality of each team’s first opponent, it’s not especially surprising that the Bears are considered underdogs for Thursday’s game.
For more on the Packers, check out Acme Packing Company. To read up on the Bears, stop by Windy City Gridiron.
Read Article >Week 2 NFL Odds: Buccaneers Vs. Giants

PresswireThe Giants have won each of the last three meetings between the two teams, including a 24-0 victory in Tampa Bay in 2009.
For more on the Giants, be sure to check out Big Blue View. To read up on the Buccaneers, stop by Bucs Nation.
Read Article >Week 2 NFL Odds: Broncos Vs. Falcons

PresswireThe over/under was initially set at 51, but it has since moved to 49, as bettors seem to be banking on more of a defensive affair.
Kickoff from the Georgia Dome is slated for the usual 8:30 p.m. ET on Monday night.
Read Article >