Skip to main content
Come Fan with UsThursday, August 6, 2026

Karlos Williams out vs. Bengals

The Bills will have LeSean McCoy back, but will be without Karlos Williams in Week 6.

Kevin Hoffman-USA TODAY Sports

Karlos Williams, the powerful and talented Bills rookie running back, will miss his second straight game this week, the team announced. Buffalo has leaned on the fifth-round pick out of Florida State recently in the wake of LeSean McCoy's hamstring injury, but Williams suffered a concussion Week 4 against the New York Giants and has not yet been cleared to return to the field.

Fortunately for the Bills, McCoy, who has missed the team’s last two games with a hamstring injury, is expected to return to the field. That means Buffalo will not be forced to rely on backups Anthony “Boobie” Dixon and Dan “Boom” Herron, like they did Week 5 against the Titans.

In that game, Dixon totaled just 19 yards on seven carries. Herron rushed for 28 yards on nine carries in his first game with the Bills.

Williams is averaging 5.4 yards per carry on 42 attempts and has scored four touchdowns in four games, despite seeing limited playing time. In three games this season, McCoy has 146 yards on the ground and seven catches for 83 yards and a receiving touchdown.

See More:

More in NFL

NFL
Caleb Williams went from viral embarrassment to perfect passes at Bears training campCaleb Williams went from viral embarrassment to perfect passes at Bears training camp
NFL

Caleb Williams’ improved accuracy was on display in a training camp drill he failed at last year

By Ricky O'Donnell
NFL
7 standout players from NFL training camp so far7 standout players from NFL training camp so far
NFL

These guys are killing it in training camp

By James Dator
NFL
Larry Fitzgerald made football look easy during NFL Hall of Fame careerLarry Fitzgerald made football look easy during NFL Hall of Fame career
NFL

Appreciating Larry Fitzgerald as he enters the Hall of Fame

By James Dator
NFL
NFL Reacts: Balancing play time in the preseasonNFL Reacts: Balancing play time in the preseason
NFL

Injuries are inevitable, but how far would you go to keep players healthy in the preaseason?

By Kyle Thele
NFL
The most impactful injuries from NFL training camp so farThe most impactful injuries from NFL training camp so far
NFL

Tracking the big injuries so far.

By James Dator
NFL
Kyle Shanahan’s car accident has transformed into the NFL’s biggest mysteryKyle Shanahan’s car accident has transformed into the NFL’s biggest mystery
NFL

A routine traffic accident has become something entirely surreal.

By James Dator