Skip to main content
Come Fan with UsWednesday, July 1, 2026

Cardinals safety Tyrann Mathieu done for the season with torn ACL

Tough break for the Cardinals as they gear up for a postseason run.

Elsa/Getty Images

The Arizona Cardinals lost defensive back Tyrann Mathieu for the season with a torn ACL, suffered in the final minutes of a 40-17 win over the Philadelphia Eagles, Cardinals head coach Bruce Arians announced on Monday.

Mathieu, 23, was in the conversation for NFL Defensive Player of the Year for his 2015 campaign with five interceptions, 16 defended passes, one forced fumble and one sack. The injury occurred on the final defensive play of the game for Arizona as Mathieu made a game-ending interception that gave the ball back to the Cardinals offense to kneel out the remainder of the clock.

Immediately after the interception, Mathieu went to the ground and held his knee and later told trainers that he felt a pop, according to NFL Network’s Ian Rapoport. Arians told Peter King of Sports Illustrated immediately after the game that the severity of the injury would be determined by an MRI on Monday.

“It could be devastating. It could be okay,” Arians said. “We just don’t know. When he came off the field, he was smiling. But the doctor said the knee’s loose.”

The Cardinals have a two-game lead over the Green Bay Packers and can clinch a first-round bye in the postseason by winning one more game. Mathieu will likely be replaced in the starting lineup by Tony Jefferson, a third-year safety with 15 career starts with the Cardinals. Jefferson tweeted words of support shortly after the news of Mathieu’s injury broke:

Mathieu suffered an ACL tear in December of his rookie year and missed one game at the beginning of the 2014 season.

See More:

More in NFL

From SBNationExternal Link
Who wins the NFC East?Who wins the NFC East?
From SBNationExternal Link
By Mark Schofield
NFL
Brendan Sorsby gets more bad news, this time from the CFLBrendan Sorsby gets more bad news, this time from the CFL
NFL

Texas Tech quarterback Brendan Sorsby has hit another hurdle on his road to the NFL

By Mark Schofield
NFL
NFL breakout candidates at every position in 2026NFL breakout candidates at every position in 2026
NFL

A team of NFL players poised to have breakout campaigns in 2026.

By Jarrett Bailey
NFL
Lions CB Terrion Arnold faces potential life in prison for alleged kidnappingLions CB Terrion Arnold faces potential life in prison for alleged kidnapping
NFL

The Detroit Lions defender faces a potential sentence of life in prison.

By James Dator
NFL
Brendan Sorsby stuck as NFL announces NO Supplemental Draft in 2026Brendan Sorsby stuck as NFL announces NO Supplemental Draft in 2026
NFL

Another setback for the QB.

By James Dator
NFL
WNFC championship game airing Sunday, June 21st from Ford Center in FriscoWNFC championship game airing Sunday, June 21st from Ford Center in Frisco
NFL

The Women’s National Football Conference Championship will air on ESPN2 this weekend.

By RJ Ochoa