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Come Fan with UsSaturday, June 20, 2026

Ohio State the favorite in Week 2’s biggest game

The Ohio State Buckeyes host the Oklahoma Sooners in a rematch of their Week 3 contest last season, with Baker Mayfield and company looking for a much different result.

NCAA Football: Ohio State at Indiana
NCAA Football: Ohio State at Indiana
Trevor Ruszkowski-USA TODAY Sports

The Ohio State Buckeyes are 9-0 straight up and 6-3 against the spread in their last nine games played in the month of September. The Buckeyes will look to get off to another strong start to the season with a win at home over the Oklahoma Sooners Saturday night.

Ohio State is a 7.5-point home favorite in Columbus at sportsbooks monitored by OddsShark.com. This will be just the 14th time since the start of the 2012 season the Buckeyes have been a single-digit favorite, and they are 10-3 SU and 9-4 ATS in their last 13 games as one.

Oklahoma Sooners at Ohio State Buckeyes

When: Saturday, Sept. 9, 7:30 p.m. ET

Where: Ohio Stadium, Columbus, Ohio

Betting Line / Total: Ohio State -7.5 / 64.5 Points

Sooners at Buckeyes OddsShark Matchup Report

Ohio State Buckeyes

In an uncharacteristically weak game on defense, Ohio State allowed 420 passing yards and 21 points last Thursday night against the Indiana Hoosiers. Still, the Hoosiers were no match for the Buckeyes, who had 596 total yards and 49 points of their own to cover the spread as 20.5-point favorites.

Ohio State’s secondary will need to perform much better this week when the Buckeyes host one of the top passing attacks in the nation.

The Buckeyes’ last September loss came at home against Virginia Tech in their first game of 2014. That was their only September home loss since 2009, as Ohio State is 22-1 SU and 15-8 ATS in its last 23 September home games per the OddsShark College Football Database.

Oklahoma Sooners

Oklahoma breezed through its tune-up game against the UTEP Miners last Saturday with a 59-7 win at home as 42.5-point favorites. Baker Mayfield put together a nice start to his Heisman Trophy resume completing 19 of his 20 passes for 329 yards and three touchdowns. Mayfield’s Sooners are 11-0 SU and 8-3 ATS in 11 games since losing to Ohio State 45-24 last season, and they’ve waited almost a full calendar year for Saturday’s shot at revenge.

Saturday’s total is set at 64.5 points. The OVER is 7-1 in Oklahoma’s last eight games on the road.

Both of these teams were legitimate playoff contenders in 2016, and it could easily be argued that Ohio State’s win over Oklahoma helped earn the Buckeyes a spot in the playoffs despite not having won the Big Ten title. Once again, the winner of this game will be in prime position for a playoff spot come bowl season.

For more info, picks and a breakdown of this week’s top sports betting news check out the new OddsShark podcast with Jon Campbell and Andrew Avery. Subscribe on iTunes, or check it out at OddsShark.libsyn.com.

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