Skip to main content
Come Fan with UsSaturday, June 20, 2026

NC State vs. Clemson odds: Key ACC matchup has big betting line at sportsbooks

The No. 3 Clemson Tigers host the No. 16 North Carolina State Wolfpack in a battle of undefeated teams this Saturday, with the sportsbooks making the Tigers heavy chalk.

Clemson v Wake Forest
Clemson v Wake Forest
Photo by Streeter Lecka/Getty Images

The No. 3 Clemson Tigers are 11-0 straight up and 5-5-1 against the spread in their last 11 games at home. The Tigers will try to pick up another home win this Saturday when they host the No. 16 North Carolina State Wolfpack.

Clemson is a 17.5-point home favorite at sportsbooks monitored by OddsShark.com. In their last six games against NC State, the Tigers are 6-0 SU with an average margin of victory of 16 points per game.

NC State Wolfpack at Clemson Tigers

When: Saturday, October 20, 3:30 p.m. ET

Where: Memorial Stadium, Clemson, South Carolina

Betting Line / Total: Clemson -17.5 / 56 Points

Wolfpack at Tigers OddsShark Matchup Report

Clemson Tigers

While Clemson was enjoying its bye week last Saturday, four teams in the top eight of the AP Top 25 lost outright. This was huge for the Tigers, who could now probably afford a regular season loss and still make the College Football Playoff.

That loss could be devastating if it came this week, however, as the winner of this game will be in the driver’s seat for the top spot in the ACC Atlantic. Clemson enters this game with the third best total defense in the nation allowing only 261 yards per game.

Despite owning a decisive 7-1 SU advantage over the Wolfpack in their last eight games against them, the Tigers are just 2-6 ATS over that stretch per the OddsShark College Football Database.

NC State Wolfpack

Ryan Finley is expected to be one of the top quarterbacks off the board in the NFL Draft next season, and he is making the most of his senior season so far. With 1,621 passing yards and 10 touchdown passes with just three interceptions, Finley has led the Wolfpack to a 5-0 SU and 3-2 ATS start to the season.

Home wins over Virginia and Boston College were both solid, but the Wolfpack will get their first real test this Saturday. NC State is just 3-12 SU and 6-9 ATS in its last 15 games as a betting underdog.

Saturday’s total is set at 56 points. The UNDER is 5-0 in Clemson’s last five home games against teams with winning records.

Both of these teams have had a bye week to prepare for this game, setting the stage for an interesting chess match between Dabo Sweeney and Dave Doeren. Clemson has the clear edge with home field advantage and the superior athletes, but look for this game to be more competitive than the spread would indicate.

For more odds information, betting picks and a breakdown of this week’s top sports betting news check out the OddsShark podcast with Jon Campbell and Andrew Avery. Subscribe on iTunes or Spotify or listen to it at OddsShark.libsyn.com.

Sports Odds, Lines And Betting News
6 Super Bowl 60 prop bet picks for Seahawks vs. Patriots6 Super Bowl 60 prop bet picks for Seahawks vs. Patriots
Sports Odds, Lines And Betting News

There are some fun prop bets on the board for Super Bowl 60

By Bill Williamson
NFL
What Super Bowl odds tell us about the final four teamsWhat Super Bowl odds tell us about the final four teams
NFL

The Seahawks head into the conference championships as the Super Bowl 60 favorite. We break down the odds of the final four teams.

By David Fucillo
NFL
Opening odds for 49ers-Seahawks in 2026 NFC Divisional roundOpening odds for 49ers-Seahawks in 2026 NFC Divisional round
NFL

The NFC Divisional round is set. We break down the opening odds for 49ers-Seahawks.

By Nick Simon
Sports Odds, Lines And Betting News
Opening odds for Rams-Bears in 2026 NFC Divisional roundOpening odds for Rams-Bears in 2026 NFC Divisional round
Sports Odds, Lines And Betting News

The NFC Divisional round is set. We break down the opening odds for Rams-Bears.

By Nick Simon
Women's College Basketball
3 women’s college basketball teams with enticing 2026 national championship odds3 women’s college basketball teams with enticing 2026 national championship odds
Women's College Basketball

UConn and South Carolina are the favorites, but other women’s college basketball teams have enticing title odds.

By Mitchell Northam
Men's College Basketball
March Madness odds: Chances for every team in the 2025 NCAA tournament to win the titleMarch Madness odds: Chances for every team in the 2025 NCAA tournament to win the title
Men's College Basketball

Cooper Flagg leads Duke to be the tournament favorite.

By James Dator and David Fucillo