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Come Fan with UsFriday, June 19, 2026

Syracuse vs. Notre Dame 2018 odds: Fighting Irish the favorites at Yankee Stadium

The No. 3 Notre Dame Fighting Irish face a red-hot opponent in the No. 12 Syracuse Orange in New York, with the sportsbooks making them double-digit favorites.

NCAA Football: Notre Dame at Northwestern
NCAA Football: Notre Dame at Northwestern
Mike DiNovo-USA TODAY Sports

The No. 3 Notre Dame Fighting Irish are 10-0 straight up and 5-4-1 against the spread with just two games remaining on their schedule. The Fighting Irish will try to keep their perfect season alive this Saturday when they take on the No. 12 Syracuse Orange in New York.

Notre Dame is a 10-point betting favorite at Yankee Stadium at sportsbooks monitored by OddsShark.com. In their last eight games played in the month of November, the Fighting Irish are 1-6-1 ATS.

Syracuse Orange vs. Notre Dame Fighting Irish

When: Saturday, November 17, 2:30 p.m. ET

Where: Yankee Stadium, Bronx, New York

Betting Line / Total: Notre Dame -10 / 61 Points

Orange vs. Fighting Irish OddsShark Matchup Report

Notre Dame Fighting Irish

With Ian Book on the shelf with an injury, Notre Dame had no issues taking care of business against a reeling Florida State Seminoles team, crushing the Seminoles at home by a score of 42-13.

Saturday’s contest against Syracuse will be a much more challenging affair and Head Coach Brian Kelly announced early in the week that Book would return to practice Tuesday and be back under center against the Orange. Book’s ability to stretch the field has made the Fighting Irish much more dangerous with him under center than Brandon Wimbush.

Since the start of the 2017 season, the Fighting Irish are 8-1 SU and 6-3 ATS in nine games against ACC opponents per the OddsShark College Football Database.

Syracuse Orange

Syracuse entered the 2018 season on the heels of three straight 4-8 SU seasons. Things have finally clicked for the Orange this year as the offense is averaging 44.4 points per game in leading the team to an 8-2 SU and 7-3 ATS record.

The Orange have two outright upsets under their belt this season in wins over Florida and North Carolina State, and they also pushed Clemson to the limit on the road in a 27-23 loss as 24.5-point underdogs.

Saturday’s total is set at 61 points. The OVER is 6-1 in Notre Dame’s last seven games and 4-1 in Syracuse’s last five games.

A road game against the USC Trojans next Saturday still looms for the Fighting Irish, but the Trojans are having a down year this season with a 5-5 SU and 3-7 ATS record. The biggest road block between Notre Dame and a spot in the College Football Playoff is Syracuse, who could earn one of the biggest wins in program history with an upset this Saturday at Yankee Stadium.

For more odds information, betting picks and a breakdown of this week’s top sports betting news check out the OddsShark podcast with Jon Campbell and Andrew Avery. Subscribe on iTunes or Spotify or listen to it at OddsShark.libsyn.com.

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