The Minnesota Vikings are 20-4 straight up and 17-7 against the spread over their last 24 preseason games. The Vikings will try to earn a fifth straight preseason win on Saturday when they host the Arizona Cardinals.
NFL Preseason Week 3 Sat/Sun odds and betting trends
The Minnesota Vikings are the biggest favorite on the board this weekend hosting the Arizona Cardinals as touchdown chalk at sportsbooks.


Minnesota is the biggest favorite of the weekend going off at -7 on the NFL odds at sportsbooks monitored by OddsShark.com. Bettors may be tempted to take a shot on the Cardinals as 7-point dogs; Arizona is 4-2 SU and ATS in its last six preseason games, and over its current preseason run of 7-5 SU and 7-4-1 ATS only two of those losses have come by more than seven points.
The Seattle Seahawks are 3-point road favorites on Saturday visiting the Los Angeles Chargers. Seattle has lost each of its last three preseason games, but before that the Seahawks were 10-5 SU and 12-3 ATS over their previous 15. The Chargers are 1-6 SU and 2-5 ATS in their last seven preseason games against Seattle.
The New York Jets are 9-3 SU and 8-4 ATS over their last 12 preseason home games per the OddsShark NFL Database. Despite their success at home, the Jets are a three-point underdog hosting the New Orleans Saints. The Saints are 6-3 SU and 5-4 ATS over their last nine preseason games.
Rounding out Saturday’s preseason card are San Francisco vs. Kansas City (-3.5), Denver vs. the Los Angeles Rams (-2), Chicago vs. Indianapolis (-1.5) and Houston vs. Dallas (PK). Houston has dominated its preseason rivalry games against the Cowboys with a 5-2 SU and 6-1 ATS record in its last seven games against Dallas. The Cowboys got a contract extension done with Jaylon Smith this week, but are still working on new deals for Ezekiel Elliott, Dak Prescott and Amari Cooper.
The Tennessee Titans lost 22-17 at home to the New England Patriots last Saturday, falling to 1-7 SU and ATS in their last eight preseason games in the process. The Titans will try to snap a four-game preseason home losing streak as 3-point home favorites hosting the Pittsburgh Steelers in the only matchup on the board Sunday. Pittsburgh is 3-1 SU and ATS over its last four preseason road games.
NFL Preseason Week 3 Betting Lines
Arizona vs. Minnesota (-7)
San Francisco vs. Kansas City (-3.5)
Seattle (-3) vs. Los Angeles Chargers
Pittsburgh vs. Tennessee (-3)
New Orleans (-3) vs. New York Jets
Denver vs. Los Angeles Rams (-2)
Chicago vs. Indianapolis (-1.5)
Houston vs. Dallas (PK)
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