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Come Fan with UsSunday, June 21, 2026

Fantasy football waiver wire: Injuries heading into Week 5

Week 4 wasn’t too bad with the injuries and we finally saw quarterbacks stay somewhat healthy on Sunday. We break down the fantasy implications.

Week 4 was weird. The biggest injuries took place before the games. Indianapolis Colts quarterback Andrew Luck didn’t have much arm strength, so the team gave him some evaluations to determine he needed to miss time. Secondly, Buffalo Bills running back LeSean McCoy hurt his hamstring in practice and now the Bills won’t be playing him for multiple weeks until he’s 100 percent.

Besides those two, there really weren’t any big-name players suffering injuries. A couple teams, the San Diego Chargers and Houston Texans, had their receiver corps get beat up badly. Although, there really wasn’t a pickup to emerge from that mess, especially in Houston. Basically, DeAndre Hopkins and Keenan Allen just get stronger.

Let’s take a look at the other injuries with some older injuries from earlier this season:

Quarterback

Andrew Luck, Indianapolis Colts

What: Shoulder injury, missed Week 4

Analysis: He may have a partial shoulder separation, so he could miss time; it’s still very unclear, but his owners have to make other plans for now.

Running back

LeSean McCoy, Buffalo Bills

What: Aggravated hamstring injury in practice; could miss 3-4 more weeks

Analysis: The biggest injury news of the week happened before Sunday; Karlos Williams is as must-own as it gets.

Latavius Murray, Oakland Raiders

What: Minor shoulder injury

Analysis: He was benched because of a fumble, so running back Roy Helu is still worth a look in deep leagues.

Lance Dunbar, Dallas Cowboys

What: Knee injury, out for season

Analysis: The Cowboys are likely going to throw Christine Michael into the fire, but he’s only worth a look in deep leagues.

Marshawn Lynch, Seattle Seahawks

What: Hamstring, cost him most of Week 3 game, inactive Week 4

Analysis: Thomas Rawls is playing in his place. There is no word yet on his availability for Week 5

Wide receiver

Nate Washington, Houston Texans

What: Hamstring injury, likely to miss time

Analysis: It looked really bad and he could miss several games; The Texans offense is a lost cause.

Cecil Shorts III, Houston Texans

What: Dislocated shoulder

Analysis: He’s likely out for a long time; the Texans will likely kick the tires on Jaelen Strong now.

Michael Crabtree, Oakland Raiders

What: Suffered an ankle injury, doesn’t sound serious yet

Analysis: He’s had a number of ankle, foot and Achilles issues, so this isn’t good; receiver Amari Cooper is really the only reliable guy unless you want to roll the dice on Andre Holmes in very deep leagues. Although, he did return from the injury.

Stevie Johnson, San Diego Chargers

What: Hamstring strain

Analysis: He has a number of hamstring injuries in his career, so he’s likely going to miss time; you’d have to be in a very deep league to add receiver Dontrelle Inman.

Malcom Floyd, San Diego Chargers

What: Concussion

Analysis: It’s too soon to tell if he’ll miss time

Tight end

Jordan Reed, Washington

What: Suffered a concussion, could miss time; sprained MCL, could miss time; sprained his ankle, could miss time

Analysis: Man, this guy just can’t stay healthy. Derek Carrier is next up, but he’s not an option. Expect the receivers to get more work.

* * *

Injuries before Week 4

Quarterback

Ben Roethlisberger, Pittsburgh Steelers

What: Knee sprain, could miss the rest of October

Analysis: Michael Vick had some ups and downs, but he’s clearly not reliable. This also really hurts Antonio Brown, especially with Martavis Bryant coming back.

Tony Romo, Dallas Cowboys

What: Broken collarbone, expected to miss about seven more weeks.

Analysis: Brandon Weeden won’t be an option and the entire passing game is in trouble.

Running back

Tevin Coleman, Atlanta Falcons

What: Suffered a rib injury and did not return; lost starting job

Analysis: Devonta Freeman: Destroyer of Worlds

Andre Ellington, Arizona Cardinals

What: Grade 1 PCL sprain, should be back next week

Analysis: This will be a timeshare upon his return. Chris Johnson can be a cut candidate if you’re eyeing a pickup.

Marshawn Lynch, Seattle Seahawks

What: Hamstring strain, missed Week 4

Analysis: The Seahawks ruled him out on Sunday for Monday Night Football. Thomas Rawls seems like he has the backup role locked up and is worth owning in 12-team leagues.

Wide receiver

Dez Bryant, Dallas Cowboys

What: Broken fifth metatarsal in foot, out 10-12 weeks

Analysis: He might be out until the playoffs, so the Dallas passing attack is in trouble.

Charles Johnson, Minnesota Vikings

What: Rib injury, missed Week 4

Analysis: For the second year in a row, a buzzy Vikings receiver is stinking it up. Cordarrelle Patterson 2.0. The Vikings’ pass attack is non-existent, so no pickups here in most cases. Mike Wallace if you’re desperate, but the Vikes are on a bye.

Davante Adams, Green Bay Packers

What: Ankle sprain, week-to-week

Analysis: James Jones and Randall Cobb are eating, but nobody really else is.

DeSean Jackson, Washington

What: Hamstring strain, could be back next week

Analysis: A number of receivers stepped up and that could continue with tight end Jordan Reed dealing with a concussion.

Sammy Watkins, Buffalo Bills

What: Calf injury cost him Week 4

Analysis: The Bills offense was not the same even against a bad New York Giants defense. There’s no pickup here.

Breshad Perriman, Baltimore Ravens

What: Suffered a setback in pregame warmups in Week 3

Analysis: The rookie receiver will likely be a rookie receiver next year, too. He is unlikely to play this year.

Victor Cruz, New York Giants

What: ACL tear from last year

Analysis: Said he’ll play in Week 4, but he’s still not worth owning.

Tight end

Vernon Davis, San Francisco 49ers

What: Knee injury, missed Week 4

Analysis: The 49ers can’t score consistently.

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