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Come Fan with UsSaturday, June 20, 2026

Bills vs. Colts: Fantasy football projections featuring Andrew Luck, Vick Ballard, C.J. Spiller

We break down the pertinent fantasy projections for the Week 12 matchup between the Buffalo Bills and Indianapolis Colts.

Jim Rogash

The Indianapolis Colts host the Buffalo Bills in a matchup of a Colts squad looking to bounce back from a brutal loss to the Patriots, and a Bills squad looking to hang around the AFC wild card race. Both teams feature high quality fantasy football options, which could prove key with the fantasy football playoffs fast approaching. To help you prepare your fantasy football lineup for Week 12, we've got game-by-game player projections courtesy of numberFire.

Buffalo Bills

Fred Jackson is back in the Bills lineup, but he has been sufficiently supplanted by C.J. Spiller to remove most of his fantasy value now that bye weeks are complete. His value lies in only the deepest of leagues.

In the passing game, Ryan Fitzpatrick remains a high upside quarterback, but the issue of consistency will always remain. He faces a Colts defense that has their own issues with consistency, so he is a fairly solid gamble this week.

Indianapolis Colts

Coming off a tough week against the New England Patriots in which he threw three interceptions, Andrew Luck looks to bounce back at home. He has been generally strong at home and is a very solid option against a bad Bills defense. The entire Colts passing attack could be in line for big performances. Donnie Avery and T.Y. Hilton are not projected particularly high in part because it seems to often be one or the other, thus making it a roll of the dice.

As for the running game, it would appear that Vick Ballard has emerged as the No. 1 running back, although that might very well be more of a 1A designation for now. Brown is back from injury and it is entirely possible the Colts are working him back in. Or he is behind Ballard moving forward. We’ll see.

For more fantasy info, head over to the SB Nation Fantasy War Room 4-8:30 p.m. ET Monday through Thursday and 9 a.m. to 1 p.m. ET on Sunday. Check out SB Nation’s own Fantasy Football game, Pick 6!

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