Fantasy football Projections, Week 6: Broncos vs. Jaguars featuring Peyton Manning, Wes Welker and Justin Blackmon

The Week 6 match up between the Denver Broncos and Jacksonville Jaguars could turn out to be one of the biggest blowouts in football history. We've got all the fantasy projections for you, courtesy of numberFire.

Quarterback Peyton Manning is on a fantasy football run the likes of which no one has ever seen before. In five games this year, Manning has thrown for 20 touchdowns and just one interception and is averaging an unbelievable 376.8 passing yards per game. At his current pace, Manning will finish the season with 60 passing touchdowns, a mark that would eclipse his career high of 49 by a mile. He would also finish with over 6,000 passing yards, shattering his previous career high of 4,700 set back in 2010, his last season with the Indianapolis Colts.

Manning's record-breaking start the season makes any receiver in the Broncos' passing game a fantasy stud by default. Wes Welker has a touchdown in every single game and two multi-touchdown games for a total of seven this year. Although it's only averaging 63 receiving yards a game, he is as surefire as it gets when it comes to collecting receptions and touchdowns. If you own Welker, Eric Decker, Demaryius Thomas or Julius Thomas in your fantasy leagues, you should be starting them in your fantasy lineup in Week 6.

With sophomore quarterback Blaine Gabbert struggling to find his place in the NFL, the Jaguars will continue to roll with Chad Henne as their starting pivot. Henne's fantasy appeal can be attributed to the fact that he is more consistent and has a better rapport with receivers Cecil Shorts and Justin Blackmon than Gabbert. Blackmon was a top-15 wide receiver in the last 10 weeks of last season with Henne under center. He looked really good against the St. Louis Rams in Week 5, catching five passes for 136 yards, including a 67-yard touchdown. There is no doubt he will be in for big fantasy numbers in a game where the Jaguars will be forced to throw the football.

The fact that the Broncos will likely be well in control of this game after one quarter doesn't bode well for the Jaguars' already non-existent running game. Through five games this season, Maurice Jones-Drew is averaging just 41.6 yards per game on the ground this year. That mark word set him on a pace to finish with just 665 yards rushing, which would be a career low for a 16-game season.

• Week 6 fantasy football rankings: QB | RB | WR | TE | D/ST