Skip to main content
Come Fan with UsSunday, June 21, 2026

Fantasy football projections, Week 16: Colts vs. Chiefs featuring Andrew Luck, Donald Brown and Jamaal Charles

We break down the Week 16 matchup between the Indianapolis Colts and the Kansas City Chiefs.

Cary Edmondson-USA TODAY Sports

The Week 16 matchup between the Indianapolis Colts and the Kansas City Chiefs could go down to the wire. We've got all the fantasy projections for you courtesy of numberfire.

Indianapolis Colts

Quarterback Andrew Luck has been a bit up and down lately. Two weeks ago, he threw for over 300 yards and managed four touchdown passes against the Cincinnati Bengals. Other than that, he's had a rough time over the past month. The good news for Luck and his fantasy owners is that the Colts are going to the playoffs and can still improve their position if they win their final games. That means Luck has plenty of incentive to win this week.

When he's not throwing the ball, Luck will hand it off to running backs Donald Brown and Trent Richardson. The latter has done very little since coming over from the Browns in a mid-season trade. Though Brown clearly is a smarter play than Richardson, he still has to go up against an above-average run defense.

Kansas City Chiefs

Running back Jamaal Charles could be named fantasy MVP this season just based on the way he picked apart the Oakland Raiders last week. He set an NFL record catching four touchdown passes out of the backfield and finished with 195 receiving yards. He single-handedly put a lot of his fantasy owners in the finals this week with his unbelievable performance.

He should be in for more rushing yards against the Colts, who don’t defend the ground game well. If Charles can’t move the chains for whatever reason, quarterback Alex Smith will have to make up for it. He’s proven he can do well in the right situation and, despite not having a fantasy stud to toss to, Smith could be an under-the-radar fantasy starter this week, especially with the game taking place at Arrowhead Stadium.

More fantasy football news from SB Nation:

Get live advice daily in the Fantasy War Room

Today’s fantasy football player updates

Week 15 fantasy football position rankings: QB | RB | WR | TE | D/ST

Week 16 fantasy football waiver wire advice: QB | RB | WR | TE | D/ST

NFL
Best DFS picks for Patriots vs Texans in Divisional roundBest DFS picks for Patriots vs Texans in Divisional round
NFL

Chet Gresham takes us through his favorite picks for FanDuel’s Divisional round DFS matchup between the Patriots and Texans

By Chet Gresham
NFL
Best DFS picks for Bears vs Rams in Divisional roundBest DFS picks for Bears vs Rams in Divisional round
NFL

Chet Gresham takes us through his favorite picks for FanDuel’s Divisional round DFS matchup between the Bears and Rams

By Chet Gresham
NFL
Best DFS picks for Broncos vs Bills in Divisional roundBest DFS picks for Broncos vs Bills in Divisional round
NFL

Chet Gresham takes us through his favorite picks for FanDuel’s Divisional round DFS matchup between the Broncos and Bills

By Chet Gresham
NFL
Best DFS picks for Seahawks vs 49ers in Divisional roundBest DFS picks for Seahawks vs 49ers in Divisional round
NFL

Chet Gresham takes us through his favorite picks for FanDuel’s Divisional round DFS matchup between the 49ers and Seahawks

By Chet Gresham
NFL
Best DFS picks for Patriots-Chargers in Wild Card round matchupBest DFS picks for Patriots-Chargers in Wild Card round matchup
NFL

Chet Gresham takes us through his favorite picks for FanDuel’s Wild Card matchup between the Patriots and Chargers

By Chet Gresham
NFL
Best DFS picks for Jaguars-Bills in the Wild Card round matchupBest DFS picks for Jaguars-Bills in the Wild Card round matchup
NFL

Chet Gresham takes us through his favorite picks for FanDuel’s Wild Card DFS matchup between the Jaguars and Bills

By Chet Gresham