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Come Fan with UsFriday, July 17, 2026

NFL Picks Week 3: 49ers Vs. Bengals

The San Francisco 49ers head to the Eastern time zone to take on the Cincinnati Bengals in what could be one of the tightest matchups of the weekend.

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The San Francisco 49ers take on the Cincinnati Bengals in Cincinnati this week and, if truth be told, this probably isn't one of the marquee matchups of the weekend. It could be one of the tightest matchups, however, with the Bengals entering as 2.5-point favorites and experts divided as to which way the game will go.

SB Nation's Andrew Sharp likes the home team, giving us a sobering reminder that Michael Crabtree used to be really good, doing things like this while he was at Texas Tech.

ESPN’s panel of experts were divided down the middle, with fans providing the decisive vote in favor of the 49ers. Accuscore took San Francisco as well, but by the slimmest of margins, predicting a final score of 19.3-19.0.

CBSSports is firmly in the Bengals’ camp, with four votes for Cincinnati to one for San Francisco among the panel of five experts. Pete Prisco took the home team by three points, saying that the long travel distance could throw off the 49ers.

Peter King, meanwhile, likes the Bengals big. He also says you should go away if you don’t know who Andy Dalton is.

For those keeping score at home, that’s 10 expert votes for the Bengals to six for the 49ers. Home field advantage appears to be the deciding factor in this one, with both teams coming off of poor performances in losing efforts last week.

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