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Come Fan with UsSaturday, June 20, 2026

Week 12 NFL odds: Panthers vs. Eagles

The Panthers opened as favorites on the road over the struggling Eagles.

The Carolina Panthers started the week favored by 2.5 on the road against the Philadelphia Eagles in Week 12. The money has since been coming in on the Eagles' side, as the line has swung to Philadelphia's side at -1/2 on one site.

Both teams come in to the matchup with abysmal straight-up records. The Panthers are 2-8, while the Eagles have stumbled to 3-7. Philadelphia is even worse against the spread, at just 2-8. Carolina is 4-6 ATS overall, and 3-1 ATS on the road.

The total opened at 41. The game figures to be low-scoring, as both offenses have struggled mightily. Carolina averages just 18.4 per game, while the Eagles are even worse at 16.2. Philadelphia has went under all five games at home, while the Panthers have went over twice in four road games.

The game will be featured on Monday Night Football, and is set to kick off at 8:30 p.m. ET.

For more on the betting lines, head to OddsShark’s Eagles-Panthers odds game page.

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