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Come Fan with UsThursday, June 25, 2026

NFL odds Week 16: Colts vs. Chiefs

The Colts are favored by more than a touchdown over the Chiefs entering the two teams’ Week 16 meeting.

US PRESSWIRE

The Indianapolis Colts enter their Week 16 road game against the Kansas City Chiefs as 7.5-point favorites, according to OddsShark.com.

The point spread opened at six but has since moved. That's likely due in part to reaction over the Chiefs' paltry offensive performance Sunday against the Oakland Raiders, which is tied for last in the NFL in points per game allowed. However, despite their 9-5 record, the Colts have actually been outscored by 3.5 points per game this season, which could help one entertain the possibility of this being a trap bet. On the other side, the Chiefs have been outscored by more than two touchdowns per game, a significant mark in futility.

The over/under is set at 41.5. The Colts generally play in games that involve a lot more points than that, while the Chiefs and their foes finish with about 39 points per game, on average.

The Colts and Chiefs will kick off at 1 p.m. ET on Sunday from Arrowhead Stadium in Kansas City, Mo. The game will be televised on CBS.

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