Skip to main content
Come Fan with UsSaturday, June 20, 2026

Patrick Willis leaves game with toe injury, does not return

The depleted 49ers defense took another hit Monday night, as linebacker Patrick Willis left the game in the third quarter with a toe injury.

San Francisco 49ers linebacker Patrick Willis left Monday night's game against the St. Louis Rams with a toe injury. Willis suffered the injury late in the first half and stayed in the locker room as the Rams began their first offensive drive of the second half.

After the Rams jumped out to a 14-0 lead in the first quarter, the 49ers defense shut St. Louis down into the second half as San Francisco took a 17-14 lead. Before leaving, Willis had three tackles on the night.

He was replaced by rookie Chris Borland, who joins Michael Wilhoite. Wilhoite replaced NaVorro Bowman last January after the latter suffered torn knee ligaments.

The 49ers are already dealing with a number of injuries on defense, but there might not be a bigger absence than that of Willis. Needless to say, San Francisco can’t afford many more losses, as nearly every area of the defense is being stretched to its limit.

See More:

More in NFL

NFL
WNFC championship game airing Sunday, June 21st from Ford Center in FriscoWNFC championship game airing Sunday, June 21st from Ford Center in Frisco
NFL

The Women’s National Football Conference Championship will air on ESPN2 this weekend.

By RJ Ochoa
From SBNationExternal Link
Which fictional quarterback would you have lead your team?Which fictional quarterback would you have lead your team?
From SBNationExternal Link
By James Dator
NFL
Best bets for 2026 NFL Offensive Rookie of the YearBest bets for 2026 NFL Offensive Rookie of the Year
NFL

There are some good longer-shot options on offensive side of ball for the NFL’s Rookie of the Year.

By Bill Williamson
NFL
Brendan Sorsby is a rare chance to get a top QB cheap, and these teams should go inBrendan Sorsby is a rare chance to get a top QB cheap, and these teams should go in
NFL

This is a no-brainer for some NFL teams.

By James Dator
NFL
Fernando Mendoza has great respect for the Raiders that came before himFernando Mendoza has great respect for the Raiders that came before him
NFL

Fernando Mendoza has great respect for the Raiders that came before him

By RJ Ochoa
NFL
Brendan Sorsby intends to enter NFL Supplemental Draft, per reportsBrendan Sorsby intends to enter NFL Supplemental Draft, per reports
NFL

Texas Tech quarterback Brendan Sorsby is entering the NFL Supplemental Draft, per reports

By Mark Schofield