Skip to main content
Come Fan with UsSunday, June 21, 2026

Giants vs. 49ers 2018 live stream: Time, TV schedule, and how to watch online

It’ll be Nick Mullens vs. Eli Manning on “Monday Night Football.”

Oakland Raiders v San Francisco 49ers
Oakland Raiders v San Francisco 49ers
Photo by Daniel Shirey/Getty Images

The San Francisco 49ers will face the New York Giants in a Monday Night Football matchup for Week 10, beginning at 8:15 p.m. ET on ESPN (live streaming via WatchESPN). The 49ers sit at 2-7 on the season, while the Giants sit at 1-7 — hardly the MNF matchup we’ve all been waiting for. That said, both teams have been exciting at times this season.

The 49ers have had serious injuries hurt their team on both sides of the ball. They rank 22nd in the league in total defense, and are particularly bad at forcing turnovers, ranking 31st in the league with a turnover differential of minus-13. The Giants are ranked pretty low in that regard as well, but still much better than the 49ers at No. 23 in the league, or a minus-4 differential. In addition to their better turnover differential, the Giants also rank 16th in the league in total defense.

On the offensive side of the ball, the 49ers are ranked about middle-of-the-pack at 14th overall, despite injuries to their starting and backup quarterbacks, plus several other starters on that side of the ball. New York ranks 22nd in the league in total offense.

Nick Mullens will be the starting quarterback for the 49ers on Monday, after his debut in relief of the injured C.J. Beathard went well against the Raiders the last time out.

Below is all you need to know to watch on Monday.

Time, TV, and streaming info

  • Time: 8:15 p.m. ET
  • Location: Levi’s Stadium, Santa Clara, Calif.
  • TV: ESPN
  • Streaming: WatchESPN
  • Odds: The 49ers opened as narrow three-point favorites at home against the Giants.

Giants vs. 49ers news

Giants vs. 49ers prediction

In the Week 10 SB Nation expert picks, all of the seven making picks think the 49ers will win it, as does the OddsShark computer. To complete the picking shutout, the coin flip also landed on the 49ers.

See More:

More in NFL

NFL
WNFC championship game airing Sunday, June 21st from Ford Center in FriscoWNFC championship game airing Sunday, June 21st from Ford Center in Frisco
NFL

The Women’s National Football Conference Championship will air on ESPN2 this weekend.

By RJ Ochoa
From SBNationExternal Link
Which fictional quarterback would you have lead your team?Which fictional quarterback would you have lead your team?
From SBNationExternal Link
By James Dator
NFL
Best bets for 2026 NFL Offensive Rookie of the YearBest bets for 2026 NFL Offensive Rookie of the Year
NFL

There are some good longer-shot options on offensive side of ball for the NFL’s Rookie of the Year.

By Bill Williamson
NFL
Brendan Sorsby is a rare chance to get a top QB cheap, and these teams should go inBrendan Sorsby is a rare chance to get a top QB cheap, and these teams should go in
NFL

This is a no-brainer for some NFL teams.

By James Dator
NFL
Fernando Mendoza has great respect for the Raiders that came before himFernando Mendoza has great respect for the Raiders that came before him
NFL

Fernando Mendoza has great respect for the Raiders that came before him

By RJ Ochoa
NFL
Brendan Sorsby intends to enter NFL Supplemental Draft, per reportsBrendan Sorsby intends to enter NFL Supplemental Draft, per reports
NFL

Texas Tech quarterback Brendan Sorsby is entering the NFL Supplemental Draft, per reports

By Mark Schofield