Skip to main content
Come Fan with UsSaturday, June 20, 2026

Deebo Samuel illness update: 49ers WR ruled out for rest of Week 7 due to illness

San Francisco 49ers wide receiver Deebo Samuel is active for Week 7, but is dealing with an illness heading into the game.

Deebo Samuel Sr. #1 of the San Francisco 49ers celebrates after scoring a touchdown during the second quarter against the Seattle Seahawks at Lumen Field on October 10, 2024 in Seattle, Washington.
Deebo Samuel Sr. #1 of the San Francisco 49ers celebrates after scoring a touchdown during the second quarter against the Seattle Seahawks at Lumen Field on October 10, 2024 in Seattle, Washington.
Photo by Steph Chambers/Getty Images

UPDATE: Shortly after the team announced Samuel was questionable to return, Cam Inman spotted him on the sideline in sweats. He is done for the day. He joins Brandon Aiyuk who was ruled out with a knee injury.

Third quarter update: The team announced that Samuel is questionable to return with his illness, per Cam Inman.

Second quarter update: Samuel is headed back to the locker room three minutes before halftime, per Tim Kawakami. He has been on the field at times, but he has been ineffective and it seems unlikely we’ll see much of him the rest of the game.

First quarter update: Samuel is not seeing playing time due to his illness. He was shown on TV wearing an oxygen mask and later talking to a team doctor. Additionally, the 49ers have put a fan behind him to help cool him down, per Tom Rinaldi.


The San Francisco 49ers announced to the media on Sunday that wide receiver Deebo Samuel has an illness, but is expected to play against the Kansas City Chiefs in Week 7, per Ian Rapoport. Samuel came out with the team for early warmups, but did not come out with the team once they had their uniforms on, per Jennifer Lee Chan. He was spotted by Matt Barrows getting in his final pre-game stretch ten minutes before the 4:25 p.m. ET kickoff.

It’s unclear what illness Samuel has, but this news suggests he’ll be in the lineup when the game kicks off at 4:25 p.m. ET. If you are making a last minute fantasy football roster decision, the one concern is Samuel plays a bit but realizes he can’t go and decides to sit the rest of the game. The same holds true if you’ve bet the over on Samuel prop bets.

This all comes down to how comfortable you are with the situation. Samuel could be fine and be a key cog in the 49ers offense in this Super Bowl rematch. But frankly, your guess is as good as mine as to whether or not you should find alternatives in fantasy football. If you’ve got a solid option, it might be worth playing it safe. But you wouldn’t be judged poorly for sticking with Samuel in Week 7.

NFL
Best DFS picks for Patriots vs Texans in Divisional roundBest DFS picks for Patriots vs Texans in Divisional round
NFL

Chet Gresham takes us through his favorite picks for FanDuel’s Divisional round DFS matchup between the Patriots and Texans

By Chet Gresham
NFL
Best DFS picks for Bears vs Rams in Divisional roundBest DFS picks for Bears vs Rams in Divisional round
NFL

Chet Gresham takes us through his favorite picks for FanDuel’s Divisional round DFS matchup between the Bears and Rams

By Chet Gresham
NFL
Best DFS picks for Broncos vs Bills in Divisional roundBest DFS picks for Broncos vs Bills in Divisional round
NFL

Chet Gresham takes us through his favorite picks for FanDuel’s Divisional round DFS matchup between the Broncos and Bills

By Chet Gresham
NFL
Best DFS picks for Seahawks vs 49ers in Divisional roundBest DFS picks for Seahawks vs 49ers in Divisional round
NFL

Chet Gresham takes us through his favorite picks for FanDuel’s Divisional round DFS matchup between the 49ers and Seahawks

By Chet Gresham
NFL
Best DFS picks for Patriots-Chargers in Wild Card round matchupBest DFS picks for Patriots-Chargers in Wild Card round matchup
NFL

Chet Gresham takes us through his favorite picks for FanDuel’s Wild Card matchup between the Patriots and Chargers

By Chet Gresham
NFL
Best DFS picks for Jaguars-Bills in the Wild Card round matchupBest DFS picks for Jaguars-Bills in the Wild Card round matchup
NFL

Chet Gresham takes us through his favorite picks for FanDuel’s Wild Card DFS matchup between the Jaguars and Bills

By Chet Gresham

Comments
Loading comments
Getting the conversation ready...