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Come Fan with UsMonday, June 22, 2026

NFL Odds Week 3: Steelers Vs. Colts

The Pittsburgh Steelers are double-digit favorites over the Indianapolis Colts on Sunday night.

INDIANAPOLIS, IN - SEPTEMBER 18: Kerry Collins #5 of the Indianapolis Colts is sacked by Artis Hicks #75 of the Cleveland Browns at Lucas Oil Stadium on September 18, 2011 in Indianapolis, Indiana. (Photo by Matthew Stockman/Getty Images)
INDIANAPOLIS, IN - SEPTEMBER 18: Kerry Collins #5 of the Indianapolis Colts is sacked by Artis Hicks #75 of the Cleveland Browns at Lucas Oil Stadium on September 18, 2011 in Indianapolis, Indiana. (Photo by Matthew Stockman/Getty Images)
INDIANAPOLIS, IN - SEPTEMBER 18: Kerry Collins #5 of the Indianapolis Colts is sacked by Artis Hicks #75 of the Cleveland Browns at Lucas Oil Stadium on September 18, 2011 in Indianapolis, Indiana. (Photo by Matthew Stockman/Getty Images)
Getty Images

The NFL is a quarterback-driven league, and with Ben Roethlisberger healthy and Peyton Manning reduced to walking laps around the team's practice field, it's no surprise that our partner Odds Shark shows the Pittsburgh Steelers as being 11-point road favorites over the Indianapolis Colts this week.

Roethlisberger received a scare late in the first half of the Steelers' 24-0 win over the Seattle Seahawks last Sunday. Seahawks defensive end Raheem Brock was tripped by Steelers rookie right tackle Marcus Gilbert and crashed directly into Big Ben's right knee. Roethlisberger missed a couple of plays, but would return to finish the game and has not appeared on the team's injury report.

Meanwhile, the Colts’ quarterback situation remains a mess.

Not only is Peyton Manning out for the foreseeable future, but his 38-year-old replacement, Kerry Collins, has completed 50.7 percent of his pass attempts for 388 yards with more interceptions (2) than touchdowns (1). Collins has been sacked just five times, but has lost three fumbles through two games. Collins was also limited in Wednesday's practice with a right shoulder injury, which doesn't figure to improve against a Steelers' pass rush that got to Seahawks quarterback Tarvaris Jackson six times last week.

For more on the opening lines, head over to Odds Shark. Be sure to check out the Colts coverage at Stampede Blue, and the Steelers at Behind The Steel Curtain.

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