Skip to main content
Come Fan with UsSaturday, June 20, 2026

NFL picks Week 16: Colts vs. Chiefs

Experts weigh in on who will win the Week 16 matchup between the Colts and Chiefs.

The Indianapolis Colts will square off against the Kansas City Chiefs on Sunday in Kansas City with a chance to clinch a playoff berth, and experts around the web feel the Colts will do just that.

Indianapolis had won seven of its last eight games before losing to the Houston Texans in week 15. Behind the arm of Andrew Luck, the Colts have staged several comeback wins to earn a 9-5 record. Luck is completing 55% of his passes for 268 yards per game, which ranks eighth in the league.

The Chiefs have struggled through their 2012 campaign, winning only twice despite having a middle-of-the-road defense. Jamaal Charles leads the Kansas City rushing offense which averages 139 yards per game.

Each expert from ESPN who has recorded a prediction has sided with the Colts, including the Accuscore prediction.

Similar predictions are up at CBS Sports, with only one of eight pickers taking Kansas City, while the smaller Yahoo! sample is unanimous in predicting an Indianapolis win.

Check out the SB Nation Channel on YouTube

See More:

More in NFL

NFL
WNFC championship game airing Sunday, June 21st from Ford Center in FriscoWNFC championship game airing Sunday, June 21st from Ford Center in Frisco
NFL

The Women’s National Football Conference Championship will air on ESPN2 this weekend.

By RJ Ochoa
From SBNationExternal Link
Which fictional quarterback would you have lead your team?Which fictional quarterback would you have lead your team?
From SBNationExternal Link
By James Dator
NFL
Best bets for 2026 NFL Offensive Rookie of the YearBest bets for 2026 NFL Offensive Rookie of the Year
NFL

There are some good longer-shot options on offensive side of ball for the NFL’s Rookie of the Year.

By Bill Williamson
NFL
Brendan Sorsby is a rare chance to get a top QB cheap, and these teams should go inBrendan Sorsby is a rare chance to get a top QB cheap, and these teams should go in
NFL

This is a no-brainer for some NFL teams.

By James Dator
NFL
Fernando Mendoza has great respect for the Raiders that came before himFernando Mendoza has great respect for the Raiders that came before him
NFL

Fernando Mendoza has great respect for the Raiders that came before him

By RJ Ochoa
NFL
Brendan Sorsby intends to enter NFL Supplemental Draft, per reportsBrendan Sorsby intends to enter NFL Supplemental Draft, per reports
NFL

Texas Tech quarterback Brendan Sorsby is entering the NFL Supplemental Draft, per reports

By Mark Schofield